Kitta Takeya, Kanno-Kakibuchi Yukiko, Chiba Hiroki, Higuchi Madoka, Ouchi Mifuka, Togo Mio, Abe-Takahashi Yui, Tsukiyama Mayuko, Shinohara Nobuo
Department of Renal and Urologic Surgery, Asahikawa Medical University, Asahikawa, Japan.
Department of Urology, University of Yamanashi, Graduate School of Medical Sciences, Yamanashi, Japan.
Urol Res Pract. 2023 May;49(3):211-215. doi: 10.5152/tud.2023.22190.
Febrile urinary tract infections, which commonly occur in spina bifida patients, can cause renal dysfunction. To help prevent febrile urinary tract infection occurrence, a better understanding of any seasonal tendencies would be beneficial.
Study points evaluated included: (i) with or without febrile urinary tract infections, (ii) type of urinary management in patients with febrile urinary tract infections, (iii) number of febrile urinary tract infection occurrences, and (iv) season associated with episode. Febrile urinary tract infection was defined by medical records specifically ascribing the term and clinical presentations consistent with the diagnosis. We evaluated febrile urinary tract infection incidence per 1 person, risk odds, expected values, and chi-square analysis.
This study examined 140 patients (79 males, 61 females). The patient's age at the first visit ranged from 2 days to 43.7 years old (median: 3.0 years old). The observation period was 0.6-43.7 years (median: 11.5 years). (i) Febrile urinary tract infection occurred in 68 cases, (ii) urinary management included: full clean intermittent catheterization: 49 cases, autoaugmented bladder: 15 cases, self-voiding: 8 cases, clean intermittent catheterization + indwelling catheter at night time: 5 cases, self-voiding + clean intermittent catheterization: 4 cases, vesicocutaneostomy: 2 cases, (iii) number of febrile urinary tract infection episodes: 2 times or less: 40 cases, 3-5 times: 20 cases, over 6 times: 8 cases, and (iv) total number of febrile urinary tract infection episodes was 183, with spring: 41, summer: 44, autumn: 37, and winter: 61. Risk odds of the incidence (one season vs. the other season) were spring: 0.870 (P = .425), summer: 0.954 (P = .784), autumn: 0.755 (P = .120), and winter 1.497 (P = .009).
发热性尿路感染常见于脊柱裂患者，可导致肾功能障碍。为有助于预防发热性尿路感染的发生，更好地了解其季节性倾向将有所裨益。
评估的研究要点包括：（i）有无发热性尿路感染；（ii）发热性尿路感染患者的尿路管理类型；（iii）发热性尿路感染的发生次数；（iv）与发作相关的季节。发热性尿路感染由病历明确界定，病历中提及该术语且临床表现符合诊断。我们评估了每人发热性尿路感染的发病率、风险比、期望值及卡方分析。
本研究共检查了140例患者（男性79例，女性61例）。首次就诊时患者年龄为2天至43.7岁（中位数：3.0岁）。观察期为0.6至43.7年（中位数：11.5年）。（i）68例发生发热性尿路感染；（ii）尿路管理方式包括：完全清洁间歇性导尿：49例，自体扩大膀胱：15例，自主排尿：8例，清洁间歇性导尿+夜间留置导尿：5例，自主排尿+清洁间歇性导尿：4例，膀胱皮肤造口术：2例；（iii）发热性尿路感染发作次数：2次及以下：40例，3 - 5次：20例，6次以上：8例；（iv）发热性尿路感染发作总数为183次，其中春季：41次，夏季：44次，秋季：37次，冬季：61次。发病率的风险比（一个季节与另一个季节相比）为春季：0.870（P = 0.425），夏季：0.954（P = 0.784），秋季：0.755（P = 0.120），冬季：1.497（P = 0.009）。
