Lupetin A R
Urol Radiol. 1986;8(2):101-3. doi: 10.1007/BF02924088.
A diagnosis of paroxysmal nocturnal hemoglobinuria may be suggested with magnetic resonance imaging, based on the massive renal cortical hemosiderosis that occurs in this disease. A diffuse bilateral depression of renal cortical signal intensity will be observed that is caused mainly by a shortening of the T2 relaxation time of renal cortical protons by the paramagnetic effect of the locally increased ferric ion concentration in the proximal convoluted tubule.
基于阵发性夜间血红蛋白尿症中出现的大量肾皮质含铁血黄素沉着症，磁共振成像可能提示该疾病的诊断。会观察到肾皮质信号强度的双侧弥漫性降低，这主要是由于近端曲管中局部铁离子浓度增加产生的顺磁效应，导致肾皮质质子的T2弛豫时间缩短所致。
