Wang Hao, Zhang Jiwei, Ma Dongyue, Zhao Ziwei, Yan Bin, Wang Fu
Department of Andrology, Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, 100091, China.
Basic Clin Androl. 2023 Oct 26;33(1):27. doi: 10.1186/s12610-023-00203-0.
Red ginseng (RG) is a traditional herb commonly used in China, Korea, and other East Asian countries. Recently, it has demonstrated a better clinical value in men's reproductive health (MRH). The present review aimed to examine the effects of RG treatment on MRH.
Overall, 42 articles related to RG application in MRH were reviewed, of which 31 were animal experiments and 11 were clinical studies. Furthermore, this review analyzed the use of RG in some male reproductive diseases in clinical trials and determined the associated mechanisms of action. The mechanism of action of RG in MRH may be related to oxidative stress, regulation of sex hormones and spermatogenesis-related proteins, and anti-inflammation.
The application of RG for the treatment of male infertility, erectile dysfunction, and prostate diseases has the potential to contribute to MRH.
红参是中国、韩国和其他东亚国家常用的传统草药。最近，它在男性生殖健康（MRH）方面显示出更好的临床价值。本综述旨在研究红参治疗对MRH的影响。
总体而言，共审查了42篇与红参在MRH中的应用相关的文章，其中31篇为动物实验，11篇为临床研究。此外，本综述分析了红参在临床试验中在一些男性生殖疾病中的应用，并确定了相关的作用机制。红参在MRH中的作用机制可能与氧化应激、性激素调节和精子发生相关蛋白以及抗炎作用有关。
红参用于治疗男性不育症、勃起功能障碍和前列腺疾病有可能对MRH有所帮助。
