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印度青少年维生素D缺乏相关因素及其相对重要性:优势分析的应用

Factors Associated with Vitamin D Deficiency and Their Relative Importance among Indian Adolescents: An Application of Dominance Analysis.

作者信息

Mustafa Akif, Shekhar Chander

机构信息

International Institute for Population Sciences (IIPS), Mumbai, India.

Department of Fertility, International Institute for Population Sciences (IIPS), Mumbai, India.

出版信息

Int J Endocrinol. 2023 Oct 17;2023:4209369. doi: 10.1155/2023/4209369. eCollection 2023.

Abstract

Vitamin D deficiency is a serious issue in developing nations, including India. This study investigates the determinants of vitamin D deficiency among Indian adolescents and assesses their relative importance using dominance analysis. Data from the Comprehensive National Nutrition Survey (CNNS) conducted between 2016 and 2018 were utilized in this study. Vitamin D levels were assessed based on serum 25-hydroxyvitamin D concentration, with a sample size encompassing 13,065 adolescents aged between 10 and 19 years. Backward stepwise multivariate logistic regression was used to identify the correlates of vitamin D deficiency, and the relative importance of these factors was assessed using dominance analysis. The study identified nine predictors that were significantly associated with vitamin D deficiency at a 1% level of significance ( = 0.001). Among these factors, sex was found to be the most significant predictor, with female adolescents being 2.66 (95% CI: 95% CI: 2.39-2.96) times more likely to be vitamin D deficient compared to male adolescents. Lifestyle and behavioral factors, such as "sex," "wealth index," and "place of residence," were more dominant in predicting vitamin D deficiency than biological indicators like "BMI" and "serum creatinine." This underscores the vital role of sunlight exposure in maintaining sufficient vitamin D levels. In summary, this study sheds light on the multifaceted factors contributing to vitamin D deficiency among Indian adolescents, emphasizing the significance of targeted interventions and public health awareness campaigns to mitigate this pressing issue.

摘要

维生素D缺乏在包括印度在内的发展中国家是一个严重问题。本研究调查了印度青少年维生素D缺乏的决定因素,并使用优势分析评估了它们的相对重要性。本研究使用了2016年至2018年期间进行的全国综合营养调查(CNNS)的数据。根据血清25-羟基维生素D浓度评估维生素D水平,样本量包括13065名年龄在10至19岁之间的青少年。采用向后逐步多元逻辑回归来确定维生素D缺乏的相关因素,并使用优势分析评估这些因素的相对重要性。该研究确定了9个预测因素,它们在1%的显著性水平(=0.001)上与维生素D缺乏显著相关。在这些因素中,性别被发现是最显著的预测因素,与男性青少年相比,女性青少年维生素D缺乏的可能性高2.66倍(95%CI:2.39-2.96)。生活方式和行为因素,如“性别”、“财富指数”和“居住地点”,在预测维生素D缺乏方面比“BMI”和“血清肌酐”等生物学指标更具主导性。这突出了阳光照射在维持充足维生素D水平方面的重要作用。总之,本研究揭示了导致印度青少年维生素D缺乏的多方面因素,强调了有针对性的干预措施和公共卫生意识运动对缓解这一紧迫问题的重要性。

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