Department of Breast Surgery, Affiliated Cancer Hospital of Nanchang University, Jiangxi Cancer Hospital, The Second Affiliated Hospital of Nanchang Medical College, Jiangxi Clinical Research Center for Cancer, Nanchang, Jiangxi Province, 330029, China.
Fuzhou Medical College of Nanchang University, Fuzhou, 344000, China.
Eur J Med Res. 2023 Oct 27;28(1):461. doi: 10.1186/s40001-023-01364-4.
Breast cancer, as a daunting global health threat, has driven an exponential growth in related research activity in recent decades. An area of research of paramount importance is protein synthesis, and the analysis of specific proteins inextricably linked to breast cancer. In this article, we undertake a bibliometric analysis of the literature on breast cancer and protein synthesis, aiming to provide crucial insights into this esoteric realm of investigation. Our approach was to scour the Web of Science database, between 2003 and 2022, for articles containing the keywords "breast cancer" and "protein synthesis" in their title, abstract, or keywords. We deployed bibliometric analysis software, exploring a range of measures such as publication output, citation counts, co-citation analysis, and keyword analysis. Our search yielded 2998 articles that met our inclusion criteria. The number of publications in this area has steadily increased, with a significant rise observed after 2003. Most of the articles were published in oncology or biology-related journals, with the most publications in Journal of Biological Chemistry, Cancer Research, Proceedings of the National Academy of Sciences of the United States of America, and Oncogene. Keyword analysis revealed that "breast cancer," "expression," "cancer," "protein," and "translation" were the most commonly researched topics. In conclusion, our bibliometric analysis of breast cancer and related protein synthesis literature underscores the burgeoning interest in this research. The focus of the research is primarily on the relationship between protein expression in breast cancer and the development and treatment of tumors. These studies have been instrumental in the diagnosis and treatment of breast cancer. Sustained research in this area will yield essential insights into the biology of breast cancer and the genesis of cutting-edge therapies.
乳腺癌作为一个令全球健康面临巨大挑战的疾病，在过去几十年中推动了相关研究活动的指数级增长。一个至关重要的研究领域是蛋白质合成，以及与乳腺癌密切相关的特定蛋白质的分析。在本文中，我们对乳腺癌和蛋白质合成相关文献进行了文献计量分析，旨在为这一深奥的研究领域提供重要的见解。我们的方法是在 Web of Science 数据库中搜索 2003 年至 2022 年间标题、摘要或关键词中包含“乳腺癌”和“蛋白质合成”的文章。我们使用文献计量分析软件，探索了一系列指标，如出版物产出、引用计数、共引分析和关键词分析。我们的搜索共得到 2998 篇符合纳入标准的文章。该领域的出版物数量稳步增加，2003 年后显著上升。大多数文章发表在肿瘤学或生物学相关期刊上，发表量最多的期刊是《生物化学杂志》《癌症研究》《美国国家科学院院刊》和《癌基因》。关键词分析显示，“乳腺癌”“表达”“癌症”“蛋白质”和“翻译”是研究最多的主题。总之，我们对乳腺癌和相关蛋白质合成文献的文献计量分析强调了人们对该研究的浓厚兴趣。研究的重点主要是乳腺癌中蛋白质表达与肿瘤发生和治疗的关系。这些研究对乳腺癌的诊断和治疗具有重要意义。在该领域持续的研究将为乳腺癌的生物学和前沿治疗方法的产生提供重要的见解。
