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利伐沙班的一种罕见副作用:药物性肝损伤。

An Uncommon Side Effect of Rivaroxaban: A Drug-Induced Liver Injury.

作者信息

Karki Bhesh R, Jasaraj Ranjit B, Jha Suman K, Maisuradze Nodari, Yu Qi

机构信息

Internal Medicine, State University of New York (SUNY) Downstate Health Sciences University, New York City, USA.

Internal Medicine, Mount Sinai Hospital Medical Center of Chicago, Chicago, USA.

出版信息

Cureus. 2023 Sep 25;15(9):e45949. doi: 10.7759/cureus.45949. eCollection 2023 Sep.

Abstract

Rivaroxaban is rarely associated with drug-induced liver injury (DILI). A 57-year-old male was sent to the emergency room from an endocrine clinic for a presyncope evaluation. His exam was non-focal, and his laboratory work was remarkable for the hepatocellular pattern of liver injury. Upon detailed assessment, he was found to have DILI due to rivaroxaban. The liver function tests improved after its discontinuation. This case emphasizes the need for early recognition and timely intervention to prevent further hepatotoxicity from the culprit drug.

摘要

利伐沙班很少与药物性肝损伤(DILI)相关。一名57岁男性从内分泌诊所被送往急诊室进行晕厥前期评估。他的检查无局灶性异常,实验室检查结果显示肝细胞型肝损伤显著。经过详细评估,发现他的药物性肝损伤是由利伐沙班引起的。停用利伐沙班后肝功能检查结果有所改善。该病例强调了早期识别和及时干预以防止罪魁祸首药物进一步导致肝毒性的必要性。

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