Center for Perioperative Optimization, Department of Surgery, Herlev and Gentofte Hospital, University of Copenhagen, Borgmester Ib Juuls Vej 1, DK-2730 Herlev, Denmark.
The Late-Complication Clinic, Capital Region of Denmark, Department of Surgery, Herlev and Gentofte Hospital, University of Copenhagen, Borgmester Ib Juuls Vej 1, DK-2730 Herlev, Denmark.
Curr Oncol. 2023 Oct 20;30(10):9317-9326. doi: 10.3390/curroncol30100673.
Erectile dysfunction is a known late complication following surgery for rectal cancer. We aimed to determine the prevalence of erectile dysfunction after rectal cancer surgery and characterize it. This was a prospective observational cohort study. Data from men after surgery for rectal cancer were collected between October 2019 and April 2023. The primary outcome was the prevalence of erectile dysfunction following surgery based on the International Index of Erectile Function questionnaires, IIEF-5 and 15. Secondary outcomes were prevalence in subgroups and self-perceived erectile function. In total, 101 patients agreed to participate, while 67 patients (67%) responded after a median six-month follow-up after surgery. Based on IIEF-15, 84% of the patients had erectile dysfunction. For subgroups, 74% of patients who underwent robot-assisted surgery had erectile dysfunction, whereas all patients who underwent either laparoscopic or open surgery had erectile dysfunction ( = 0.031). Furthermore, half of the patients rated their self-perceived ability to obtain and keep an erection as very low. In conclusion, in our cohort, erectile dysfunction was common after rectal cancer surgery, and half of the patients were unconfident that they could obtain and keep an erection. Information regarding this finding should be given so that patients feel comfortable discussing therapeutic solutions if needed.
勃起功能障碍是直肠癌手术后已知的晚期并发症。我们旨在确定直肠癌手术后勃起功能障碍的患病率并对其进行特征描述。这是一项前瞻性观察性队列研究。2019 年 10 月至 2023 年 4 月期间，收集了接受直肠癌手术后男性的数据。主要结局是基于国际勃起功能指数问卷（IIEF-5 和 15）评估的手术后勃起功能障碍的患病率。次要结局是亚组中的患病率和自我感知的勃起功能。共有 101 名患者同意参与，而在手术后中位 6 个月随访后，有 67 名患者（67%）做出了回应。根据 IIEF-15，84%的患者存在勃起功能障碍。对于亚组，接受机器人辅助手术的患者中有 74%存在勃起功能障碍，而接受腹腔镜或开放手术的所有患者均存在勃起功能障碍（=0.031）。此外，一半的患者对自己获得和维持勃起的能力自评非常低。总之，在我们的队列中，直肠癌手术后勃起功能障碍很常见，有一半的患者对自己获得和维持勃起的能力缺乏信心。如果需要，应该提供有关这一发现的信息，以便患者能够舒适地讨论治疗方案。
