Kim Junyoung, Kim Kitae, Oh Dayoung, Myung Hyunwook, Choi Jihye, Yoon Junghee
N Animal Medical Center, Seoul 02732, Republic of Korea.
College of Veterinary Medicine and the Research Institute for Veterinary Science, Seoul National University, Seoul 08826, Republic of Korea.
Vet Sci. 2023 Sep 26;10(10):593. doi: 10.3390/vetsci10100593.
Infiltrative lipomas, which are locally invasive tumors composed of well-differentiated adipocytes, are histologically identical to lipomas but have a tendency to infiltrate adjacent muscle and fibrous tissue without metastasis, such as muscle; connective tissue; bone; and, in rare cases, peripheral nerves and the spinal cord. They differ from liposarcomas yet also exhibit neoplastic cell infiltration and often recur despite surgical removal. A 10-year-old spayed Maltese female dog presented with hindlimb paresis and back pain for two months. Computed tomography and magnetic resonance imaging revealed an extensive fatty mass impinging on the vertebral canal, compressing the spinal cord, and extending into the surrounding muscle layers and thoracic cavity. The mass was surgically removed, and subsequent postoperative computed tomography confirmed complete removal of the mass using Vitrea advanced visualization fat measurement. Histopathological analysis confirmed that the mass was an infiltrative lipoma. The patient's symptoms completely resolved after surgery, with no recurrence reported at the 2-year follow-up. This case highlights the benefits of using postoperative computed tomography combined with the automated fat measurement technique to determine whether reoperation is necessary or to predict patient prognosis by identifying potential residual lipoma post-surgery.
浸润性脂肪瘤是由分化良好的脂肪细胞组成的局部侵袭性肿瘤，在组织学上与脂肪瘤相同，但有浸润相邻肌肉和纤维组织而不发生转移的倾向，如肌肉、结缔组织、骨骼，在罕见情况下还可浸润周围神经和脊髓。它们与脂肪肉瘤不同，但也表现出肿瘤细胞浸润，并且尽管手术切除后仍常复发。一只10岁绝育的雌性马尔济斯犬出现后肢轻瘫和背痛两个月。计算机断层扫描和磁共振成像显示一个广泛的脂肪肿块压迫椎管，压迫脊髓，并延伸至周围肌肉层和胸腔。该肿块经手术切除，术后计算机断层扫描使用Vitrea高级可视化脂肪测量法确认肿块已完全切除。组织病理学分析证实该肿块为浸润性脂肪瘤。患者术后症状完全缓解，2年随访未报告复发。本病例强调了术后计算机断层扫描结合自动脂肪测量技术在确定是否需要再次手术或通过识别术后潜在残留脂肪瘤来预测患者预后方面的益处。
