Foong Daphne, Calder Stefan, Varghese Chris, Schamberg Gabriel, Xu William, Daker Charlotte, Ho Vincent, Andrews Christopher N, Gharibans Armen A, O'Grady Greg
School of Medicine, Western Sydney University, Campbelltown, NSW 2560, Australia.
Department of Surgery, Auckland City Hospital, Auckland 1023, New Zealand.
J Clin Med. 2023 Oct 10;12(20):6436. doi: 10.3390/jcm12206436.
Chronic gastroduodenal symptoms are prevalent worldwide, and there is a need for new diagnostic and treatment approaches. Several overlapping processes may contribute to these symptoms, including gastric dysmotility, hypersensitivity, gut-brain axis disorders, gastric outflow resistance, and duodenal inflammation. Gastric Alimetry (Alimetry, New Zealand) is a non-invasive test for evaluating gastric function that combines body surface gastric mapping (high-resolution electrophysiology) with validated symptom profiling. Together, these complementary data streams enable important new clinical insights into gastric disorders and their symptom correlations, with emerging therapeutic implications. A comprehensive database has been established, currently comprising > 2000 Gastric Alimetry tests, including both controls and patients with various gastroduodenal disorders. From studies employing this database, this paper presents a systematic methodology for Gastric Alimetry test interpretation, together with an extensive supporting literature review. Reporting is grouped into four sections: Test Quality, Spectral Analysis, Symptoms, and Conclusions. This review compiles, assesses, and evaluates each of these aspects of test assessment, with discussion of relevant evidence, example cases, limitations, and areas for future work. The resultant interpretation methodology is recommended for use in clinical practice and research to assist clinicians in their use of Gastric Alimetry as a diagnostic aid and is expected to continue to evolve with further development.
慢性胃十二指肠症状在全球普遍存在，因此需要新的诊断和治疗方法。有几个相互重叠的过程可能导致这些症状，包括胃动力障碍、超敏反应、肠-脑轴紊乱、胃流出道阻力和十二指肠炎症。胃测压法（新西兰Alimetry公司）是一种评估胃功能的非侵入性检测方法，它将体表胃电图（高分辨率电生理学）与经过验证的症状分析相结合。这些互补的数据流共同为胃疾病及其症状相关性提供了重要的新临床见解，并具有新出现的治疗意义。已经建立了一个综合数据库，目前包含超过2000次胃测压法检测，包括对照组和患有各种胃十二指肠疾病的患者。本文从使用该数据库的研究中，提出了一种系统的胃测压法检测解读方法，并进行了广泛的支持性文献综述。报告分为四个部分：检测质量、频谱分析、症状和结论。本综述对检测评估的这些方面进行了汇编、评估和评价，并讨论了相关证据、实例、局限性和未来工作领域。建议将所得的解读方法用于临床实践和研究，以帮助临床医生使用胃测压法作为诊断辅助手段，并且随着进一步发展有望持续演变。
