Golovin Denis A, Rostovtseva Tatyana M, Kudryavtsev Yuri S, Berdalin Alexander B, Lelyuk Svetlana E, Lelyuk Vladimir G
Department of Clinical and Experimental Physiology of Circulatory System, Ultrasound and Functional Diagnostics of Federal State Budgetary Institution, Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency Russian Federation, 123182 Moscow, Russia.
Federal State Budgetary Educational Institution, Further Professional Education "Russian Medical Academy of Continuous Professional Education", Ministry of Healthcare of the Russian Federation, 127051 Moscow, Russia.
Biomedicines. 2023 Oct 11;11(10):2751. doi: 10.3390/biomedicines11102751.
Carotid artery elongation (ECA) is widespread in the asymptomatic population and among people with a history of ischemic stroke (IS). There are different points of view on the ways these changes contribute to brain ischemic damage pathogenesis. Materials and Methods: From 2019 to 2021, we included 1171 people who had suffered from IS less than one year before the investigation in the study, 404 (34.5%) women aged 27 to 95 years (64 ± 13 years) and 767 men (21-90; 60 ± 11 years). All patients involved in the study underwent multimodal radiological investigation in addition to assessments of their clinical and neurological data. Results: In this study, we were unable to detect a relationship between ECA localization and acute ischemic lesions. The frequency of ECA detection in patients with IS was the same as that in carotid and vertebral-basilar arterial systems. The prevalence of ECA was the same in patients with different IS subtypes (TOAST). There was no association between the localization of ECA and ischemic lesions; moreover, there were no differences in the IS frequency between anterior and posterior circulation. There were statistically significant decreases in linear peak systolic and end diastolic velocities in the internal carotid and vertebral arteries, as well as in the intracranial arteries in patients with ECA.
颈动脉延长（ECA）在无症状人群和有缺血性卒中（IS）病史的人群中普遍存在。关于这些变化如何导致脑缺血损伤发病机制，存在不同观点。材料与方法：2019年至2021年，我们纳入了1171名在调查前不到一年患IS的人群，其中404名（34.5%）女性，年龄在27至95岁（64±13岁），767名男性（21 - 90岁；60±11岁）。除了评估临床和神经学数据外，所有参与研究的患者均接受了多模态放射学检查。结果：在本研究中，我们未能检测到ECA定位与急性缺血性病变之间的关系。IS患者中ECA的检出频率与颈动脉和椎基底动脉系统相同。不同IS亚型（TOAST）患者中ECA的患病率相同。ECA的定位与缺血性病变之间无关联；此外，前后循环的IS频率无差异。ECA患者的颈内动脉、椎动脉以及颅内动脉的线性收缩期峰值和舒张末期速度有统计学意义的降低。
