Huang Huan, Fu Jian-Jiong, Yao Pi-Guang, Wang Meng-Yao, Wang Xue, Guo An-Na, Li Wei, Chen Shao-Huai, Li Dan-Dong
Department of Radiology and the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Department of Neurology, Zhuji Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang, China.
Front Neurol. 2024 Mar 11;15:1307984. doi: 10.3389/fneur.2024.1307984. eCollection 2024.
Tortuosity of the carotid artery is a common angiographic finding that may impact blood flow and neuronal function. However, information on its prevalence and risk factors remains limited. In this study, we determined to explore the factors affecting carotid artery tortuosity.
The head and neck computed tomography angiography (CTA) imaging and cerebral angiography data performed at the Second Affiliated Hospital of Wenzhou Medical University between January 2019 and September 2021 were collected, and a total of 356 cases were enrolled in the study after screening. Carotid artery tortuosity refers to the angle between the two adjacent segments of the carotid artery, from the opening of the aortic arch on either side to the external orifice of the carotid canal, being less than 150°. A retrospective analysis was performed to compare the general information, laboratory indicators, personal history, and medical history between the two groups. The χ test, -test, and Mann-Whitney -test were performed to compare the parameters between the two groups. If there were significant differences between the groups, multivariate logistic regression was performed to analyze the factors affecting carotid artery tortuosity.
A total of 222 of the 356 cases were determined to have carotid artery tortuosity, accounting for 63.6%. There were statistically significant differences in age, body mass index (BMI), duration of diabetes and hypertension, levels of low-density lipoprotein cholesterol (LDL-C), diastolic blood pressure, history of ischemic and hemorrhagic stroke, and the usage of antihypertensive drugs between the two groups. Multivariate logistic regression analysis of the above factors showed that age (OR = 5.063, 95% CI 2.963-10.26, < 0.001) and duration of hypertension (OR = 2.356, 95% CI 1.353-8.625, = 0.021) were associated with a higher incidence of carotid artery tortuosity. Compared to patients who did not consume antihypertensive drugs, the incidence of carotid artery tortuosity was significantly less (OR = 0.094, 95% CI 0.002-0.713, = 0.019) in those consuming antihypertensive drugs.
Carotid artery tortuosity is a relatively common carotid artery disease. The incidence of carotid artery tortuosity may increase with age and the duration of hypertension. The consumption of antihypertensive drugs may reduce the incidence of carotid artery tortuosity.
颈动脉迂曲是一种常见的血管造影表现，可能影响血流和神经功能。然而，关于其患病率和危险因素的信息仍然有限。在本研究中，我们旨在探讨影响颈动脉迂曲的因素。
收集温州医科大学附属第二医院2019年1月至2021年9月期间进行的头颈部计算机断层扫描血管造影（CTA）成像和脑血管造影数据，经筛选后共纳入356例患者进行研究。颈动脉迂曲是指从两侧主动脉弓开口至颈动脉管外口的颈动脉相邻两段之间的夹角小于150°。进行回顾性分析以比较两组之间的一般信息、实验室指标、个人史和病史。采用χ²检验、t检验和Mann-Whitney U检验比较两组参数。如果两组之间存在显著差异，则进行多因素logistic回归分析以分析影响颈动脉迂曲的因素。
356例患者中共有222例被确定为颈动脉迂曲，占63.6%。两组在年龄、体重指数（BMI）、糖尿病和高血压病程、低密度脂蛋白胆固醇（LDL-C）水平、舒张压、缺血性和出血性卒中病史以及降压药物使用情况方面存在统计学显著差异。对上述因素进行多因素logistic回归分析显示，年龄（OR = 5.063，95%CI 2.963 - 10.26，P < 0.001）和高血压病程（OR = 2.356，95%CI 1.353 - 8.625，P = 0.021）与颈动脉迂曲的较高发生率相关。与未服用降压药物的患者相比，服用降压药物的患者颈动脉迂曲的发生率显著降低（OR = 0.094，95%CI 0.002 - 0.713，P = 0.019）。
颈动脉迂曲是一种相对常见的颈动脉疾病。颈动脉迂曲的发生率可能随年龄和高血压病程的增加而升高。服用降压药物可能降低颈动脉迂曲的发生率。
