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小儿基底动脉闭塞成功进行机械取栓术:一例报告

Successful Mechanical Thrombectomy for Basilar Artery Occlusion in a Pediatric Patient: A Case Report.

作者信息

Teivāne Agnete, Naļivaiko Inga, Jurjāns Kristaps, Vētra Jānis, Veiss Andris, Novaša Arina, Dzelzīte Sarmīte, Krieviņš Dainis, Miglāne Evija

机构信息

Faculty of Residency, Riga Stradins University, LV-1007 Riga, Latvia.

Neurology Department, Pauls Stradins Clinical University Hospital, LV-1002 Riga, Latvia.

出版信息

Biomedicines. 2023 Oct 13;11(10):2774. doi: 10.3390/biomedicines11102774.

DOI:10.3390/biomedicines11102774
PMID:37893148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10603831/
Abstract

Studies have shown the benefits of endovascular treatment (EVT) in adult stroke cases, but its application in pediatric stroke remains controversial. Despite evidence of improved outcomes in adults, there are no established recommendations for EVT in children. Conducting individual case reports and case series is vital to understanding its potential advantages and disadvantages in this context. In this case report, a 9-year-old male initially diagnosed with gastroenteritis developed sudden left-sided weakness 1 day after admission. Comprehensive imaging revealed acute ischemia in the cerebellum, indicating a basilar artery thrombus. Urgent endovascular treatment (EVT) was performed 8.5 h after the onset of neurological symptoms, achieving successful revascularization. The patient underwent rehabilitation and was later discharged with improved neurological status. Despite extensive investigations, the stroke's origin remained unknown. After six months, the patient exhibited complete neurological recovery, highlighting the patient's remarkable resilience.

摘要

研究表明血管内治疗(EVT)在成人中风病例中具有益处,但其在儿童中风中的应用仍存在争议。尽管有证据表明成人接受该治疗后预后有所改善,但目前尚无针对儿童EVT的既定建议。开展个案报告和病例系列研究对于了解其在这种情况下的潜在优缺点至关重要。在本病例报告中,一名9岁男性最初被诊断为肠胃炎,入院1天后突然出现左侧肢体无力。综合影像学检查显示小脑急性缺血,提示基底动脉血栓形成。在神经症状发作8.5小时后进行了紧急血管内治疗(EVT),实现了成功的血管再通。患者接受了康复治疗,后来出院时神经状态有所改善。尽管进行了广泛的调查,中风的病因仍然不明。六个月后,患者实现了完全神经功能恢复,凸显了患者显著的恢复能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41aa/10603831/669b1775a94f/biomedicines-11-02774-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41aa/10603831/627ab0bab57a/biomedicines-11-02774-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41aa/10603831/e295e3a0dc02/biomedicines-11-02774-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41aa/10603831/5c7488e0f54a/biomedicines-11-02774-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41aa/10603831/669b1775a94f/biomedicines-11-02774-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41aa/10603831/627ab0bab57a/biomedicines-11-02774-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41aa/10603831/e295e3a0dc02/biomedicines-11-02774-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41aa/10603831/5c7488e0f54a/biomedicines-11-02774-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/41aa/10603831/669b1775a94f/biomedicines-11-02774-g005.jpg

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Stroke. 2019 Mar;50(3):e51-e96. doi: 10.1161/STR.0000000000000183.
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Pediatric Stroke Rates Over 17 Years: Report From a Population-Based Study.
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J Child Neurol. 2018 Jun;33(7):463-467. doi: 10.1177/0883073818767039. Epub 2018 Apr 19.
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Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials.血管内血栓切除术治疗大动脉闭塞性缺血性卒中的Meta 分析:来自五项随机试验的个体患者数据汇总分析
Lancet. 2016 Apr 23;387(10029):1723-31. doi: 10.1016/S0140-6736(16)00163-X. Epub 2016 Feb 18.
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Exome sequencing explained: a practical guide to its clinical application.外显子组测序解析:临床应用实用指南
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