Lehman Laura L, Khoury Jane C, Taylor J Michael, Yeramaneni Samrat, Sucharew Heidi, Alwell Kathleen, Moomaw Charles J, Peariso Katrina, Flaherty Matthew, Khatri Pooja, Broderick Joseph P, Kissela Brett M, Kleindorfer Dawn O
1 Department of Neurology, Boston Children's Hospital, MA, USA.
2 Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
J Child Neurol. 2018 Jun;33(7):463-467. doi: 10.1177/0883073818767039. Epub 2018 Apr 19.
We previously published rates of pediatric stroke using our population-based Greater Cincinnati Northern Kentucky Stroke Study (GCNK) for periods July 1993-June 1994 and 1999. We report population-based rates from 2 additional study periods: 2005 and 2010. We identified all pediatric strokes for residents of the GCNK region that occurred in July 1, 1993-June 30, 1994, and calendar years 1999, 2005, and 2010. Stroke cases were ascertained by screening discharge ICD-9 codes, and verified by a physician. Pediatric stroke was defined as stroke in those <20 years of age. Stroke rates by study period, overall, by age and by race, were calculated. Eleven children died within 30 days, yielding an all-cause case fatality rate of 15.7% (95% confidence interval 1.1%, 26.4%) with 3 (27.3%) ischemic, 6 (54.5%) hemorrhagic, and 2 (18.2%) unknown stroke type. The pediatric stroke rate of 4.4 per 100 000 in the GCNK study region has not changed over 17 years.
我们之前利用基于人群的大辛辛那提北肯塔基卒中研究（GCNK）公布了1993年7月至1994年6月以及1999年期间的儿童卒中发病率。我们报告另外两个研究时间段（2005年和2010年）基于人群的发病率。我们确定了GCNK地区居民在1993年7月1日至1994年6月30日、1999年、2005年和2010年发生的所有儿童卒中病例。通过筛查出院ICD - 9编码确定卒中病例，并由医生进行核实。儿童卒中定义为年龄小于20岁者发生的卒中。计算了各研究时间段、总体、按年龄和按种族的卒中发病率。11名儿童在30天内死亡，全因病死率为15.7%（95%置信区间1.1%，26.4%），其中3例（27.3%）为缺血性卒中，6例（54.5%）为出血性卒中，2例（18.2%）卒中类型不明。GCNK研究地区每10万人中4.4例的儿童卒中发病率在17年中未发生变化。
