Moneret-Vautrin D A, Faure G, Bene M C
Allergy. 1986 Sep;41(7):546-8. doi: 10.1111/j.1398-9995.1986.tb00342.x.
This paper reports the case of a young female patient who presented with a cutaneous urticarial disseminated eruption. Drug-induced side effects were eliminated, and the only recent dietary change was the regular use of chewing-gums containing chlorophylla (E140), menthol and BHT (butylhydroxytoluene). Immunohistological analysis of a cutaneous lesion revealed signs of vasculitis. Within 1 week after stopping chewing gum, the eruption subsided. Oral provocation tests at 4-day intervals confirmed the responsibility of BHT by the reinduction of the cutaneous signs after a few hours.
本文报告了一名年轻女性患者的病例，该患者出现了皮肤荨麻疹弥漫性皮疹。排除了药物引起的副作用，近期唯一的饮食变化是经常食用含有叶绿素（E140）、薄荷醇和丁基羟基甲苯（BHT）的口香糖。对皮肤病变进行的免疫组织学分析显示有血管炎迹象。停止嚼口香糖后1周内，皮疹消退。每隔4天进行的口服激发试验证实，几小时后皮肤症状再次出现是由BHT引起的。
