Strube P J, Hallam P L
Anaesthesia. 1986 Oct;41(10):1017-9. doi: 10.1111/j.1365-2044.1986.tb12744.x.
A 13-year-old girl was admitted to the intensive care unit with status asthmaticus. Conventional bronchodilator therapy failed to relieve her bronchospasm. In order to try and avoid artificial ventilation, a continuous intravenous infusion of ketamine was used with success. The total dose rate was 40 micrograms/kg minute for a period of 8 hours; this was given at a decreasing rate. She regained consciousness 30 minutes after the end of the infusion and became well orientated after one hour. Ketamine is a useful drug in the intensive treatment of status asthmaticus and should be tried before a decision is taken to start mechanical ventilation.
一名13岁女孩因哮喘持续状态入住重症监护病房。常规支气管扩张剂治疗未能缓解她的支气管痉挛。为了尽量避免人工通气，使用了氯胺酮持续静脉输注并取得成功。总剂量率为每分钟40微克/千克，持续8小时；以递减速率给药。输注结束后30分钟她恢复意识，1小时后定向力良好。氯胺酮在哮喘持续状态的强化治疗中是一种有用的药物，在决定开始机械通气之前应尝试使用。
