Lew J K, Eastley R J, Hanning C D
Anaesthesia. 1986 Nov;41(11):1092-7. doi: 10.1111/j.1365-2044.1986.tb12955.x.
Oxyhaemoglobin saturation was monitored continuously during electroconvulsive therapy in two groups of patients. All patients were anaesthetised using methohexitone (40-100 mg) and suxamethonium (25-50 mg). In group 1 (n = 48), the patients' lungs were ventilated manually with oxygen in air (40-50%) during the modified convulsion. In group 2 (n = 47), the convulsion was allowed to subside before recommencing manual ventilation with a similar gas mixture. Eight patients in group 1 and seven patients in group 2 received more than one shock and were excluded, leaving 40 patients in each group. In group 1, one patient had a minimum oxygen saturation of less than 90% after the electric shock as opposed to 11 in group 2 (p less than 0.01). Five of the patients in group 2 had a saturation of less than 80%. It is concluded that patients undergoing electroconvulsive therapy should be ventilated with an oxygen-enriched gas mixture during the convulsion induced by the electric shock in order to avoid hypoxaemia.
在两组患者接受电休克治疗期间持续监测氧合血红蛋白饱和度。所有患者均使用美索比妥(40 - 100毫克)和琥珀酰胆碱(25 - 50毫克)进行麻醉。在第1组(n = 48)中,在改良惊厥期间用含40 - 50%氧气的空气手动对患者肺部进行通气。在第2组(n = 47)中,在惊厥平息后再用类似的气体混合物重新开始手动通气。第1组中有8名患者和第2组中有7名患者接受了不止一次电击并被排除,每组各剩下40名患者。在第1组中,有1名患者在电击后最低氧饱和度低于90%,而在第2组中有11名患者出现这种情况(p < 0.01)。第2组中有5名患者饱和度低于80%。得出的结论是,接受电休克治疗的患者在电击诱发惊厥期间应以富氧气体混合物进行通气,以避免低氧血症。