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丙泊酚用于电休克治疗:与美索比妥的比较。初步报告

Propofol for electroconvulsive therapy. A comparison with methohexitone. Preliminary report.

作者信息

Rouse E C

机构信息

Glan Clwyd Hospital, Bodelwyddan, North Wales.

出版信息

Anaesthesia. 1988 Mar;43 Suppl:61-4. doi: 10.1111/j.1365-2044.1988.tb09073.x.

DOI:10.1111/j.1365-2044.1988.tb09073.x
PMID:3259100
Abstract

Twenty patients who received electroconvulsive therapy were anaesthetised with either propofol or methohexitone in a randomised crossover study. Recovery times were similar but patients who received propofol tended to be orientated sooner. The decrease in arterial blood pressure after induction was greater with propofol than with methohexitone. There was an increase in blood pressure immediately after therapy in patients who received methohexitone but not in those given propofol. There was a slight difference in pain on injection. The mean duration of convulsion (measured in 10 patients) during anaesthesia was shorter with propofol than with methohexitone.

摘要

在一项随机交叉研究中,20名接受电休克治疗的患者分别使用丙泊酚或美索比妥进行麻醉。恢复时间相似,但接受丙泊酚的患者定向更快。诱导后丙泊酚组动脉血压下降幅度大于美索比妥组。接受美索比妥治疗的患者治疗后血压立即升高,而丙泊酚组则未出现这种情况。注射时疼痛略有差异。麻醉期间抽搐的平均持续时间(在10名患者中测量)丙泊酚组短于美索比妥组。

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引用本文的文献

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J Anaesthesiol Clin Pharmacol. 2012 Jul;28(3):353-7. doi: 10.4103/0970-9185.98337.
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Propofol. An update of its use in anaesthesia and conscious sedation.丙泊酚。其在麻醉和清醒镇静中应用的最新情况。
Drugs. 1995 Sep;50(3):513-59. doi: 10.2165/00003495-199550030-00008.
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Excitatory events associated with propofol anaesthesia: a review.与丙泊酚麻醉相关的兴奋性事件:综述
J R Soc Med. 1992 May;85(5):288-91. doi: 10.1177/014107689208500516.