Department of General Surgery, Drum Tower Medical College of Nanjing Medical University, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China.
Department of General Surgery, Drum Tower Hospital, Medical School of Nanjing University, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, China.
World J Surg Oncol. 2021 Sep 9;19(1):271. doi: 10.1186/s12957-021-02385-1.
The safety and efficacy of indocyanine green (ICG) imaging navigational laparoscopic gastrectomy remain controversial. This study is to evaluate the short-term and long-term outcomes of ICG-guided laparoscopic radial gastrectomy in patients with gastric cancer.
Consecutive patients with definitive diagnosis of gastric cancer that underwent laparoscopic radical gastrectomy were collected retrospectively. Propensity score matching (PSM) at 1:1 ratio was performed to compare the outcomes of two groups.
A total of 122 qualified patients were divided into ICG group (n = 34) and non-ICG group (n = 88). PSM yielded 28 patients with comparable baseline characteristics into each group. The number of retrieved lymph node in ICG group was significantly higher than that in non-ICG group (P = 0.0196). There was no statistical difference of perioperative, short-term, and long-term complications between the two groups.
ICG-guided laparoscopic radical gastrectomy is safe and effective, and ICG-navigated lymphadenectomy improves the number of retrieved lymph nodes for patients with gastric cancer.
吲哚菁绿（ICG）成像导航腹腔镜胃切除术的安全性和有效性仍存在争议。本研究旨在评估 ICG 引导腹腔镜胃放射状切除术治疗胃癌的短期和长期疗效。
回顾性收集了经明确诊断为胃癌并行腹腔镜根治性胃切除术的连续患者。采用 1:1 比例的倾向评分匹配（PSM）比较两组患者的结局。
共纳入 122 例符合条件的患者，分为 ICG 组（n=34）和非-ICG 组（n=88）。PSM 后每组各有 28 例患者具有可比的基线特征。ICG 组的淋巴结检出数量明显多于非-ICG 组（P=0.0196）。两组患者的围手术期、短期和长期并发症无统计学差异。
ICG 引导腹腔镜根治性胃切除术安全有效，ICG 导航淋巴结清扫术可增加胃癌患者的淋巴结检出数量。
