University of Coimbra, Faculty of Pharmacy, Polo III, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.
National Institute for Agricultural and Veterinary Research (INIAV), I.P., 4485-655 Vila do Conde, Portugal.
Molecules. 2023 Oct 23;28(20):7233. doi: 10.3390/molecules28207233.
Ergot alkaloids are secondary metabolites resulting from fungi of the genus that have proven to be highly toxic. These mycotoxins commonly infect cereal crops such as wheat, rye, barley, and oats. Due to the increase worldwide consumption of cereal and cereal-based products, the presence of ergot alkaloids in food presents a concern for human safety. For this reason, it is essential to develop several analytical methods that allow the detection of these toxic compounds. This review compiles and discusses the most relevant studies and methods used in the detection and quantification of ergot alkaloids. Moreover, the decontamination techniques are also addressed, with special attention to sorting, cleaning, frying, baking, peeling, and ammonization methods, as they are the only ones already applied to ergot alkaloids.
麦角生物碱是真菌属产生的次生代谢物,已被证明具有高度毒性。这些霉菌毒素通常感染小麦、黑麦、大麦和燕麦等谷物作物。由于全球对谷物和谷物制品的消费增加,食品中麦角生物碱的存在对人类安全构成了关注。出于这个原因,开发几种允许检测这些有毒化合物的分析方法至关重要。这篇综述汇集并讨论了在检测和定量麦角生物碱方面最相关的研究和方法。此外,还讨论了脱污染技术,特别关注分类、清洁、油炸、烘烤、去皮和氨化方法,因为这些方法是唯一已经应用于麦角生物碱的方法。