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通过喷雾干燥法对负载香叶醇的乳液进行微囊化,该乳液由海洋胞外多糖稳定以增强抗菌活性。

Microencapsulation via Spray-Drying of Geraniol-Loaded Emulsions Stabilized by Marine Exopolysaccharide for Enhanced Antimicrobial Activity.

作者信息

Joulak Ichrak, Azabou Samia, Dumas Emilie, Freitas Filomena, Attia Hamadi, Gharsallaoui Adem

机构信息

Laboratoire Analyse Valorisation et Sécurité des Aliments, Université de Sfax, ENIS, Sfax 3038, Tunisia.

CNRS, LAGEPP UMR 5007, University of Lyon, Université Claude Bernard Lyon 1, 43 Bd 11 Novembre 1918, 69622 Villeurbanne, France.

出版信息

Life (Basel). 2023 Sep 25;13(10):1958. doi: 10.3390/life13101958.

DOI:10.3390/life13101958
PMID:37895340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10608584/
Abstract

The current study investigates the formation of microencapsulated geraniol powder, with the exopolysaccharide EPS-K1B3 produced by K1, as wall material, using spray-drying. Evaluation of the antimicrobial activity of the functional emulsions, prepared at either pH 5 or pH 7, was carried out against Gram-positive ( (ATCC 33090)) and Gram-negative ( (DSM682)) bacterial strains. Results showed prolonged antimicrobial efficacy until 30 days of incubation for geraniol microcapsules compared to wet geraniol emulsions, which could confirm the ability of the spray-drying process to protect encapsulated geraniol for a longer period. The highest antimicrobial efficacy of geraniol microcapsules was observed against at pH 5. Therefore, the influence of pH on the functional property of geraniol microcapsules could be highlighted beside the targeted bacterial strain.

摘要

本研究采用喷雾干燥法,以K1产生的胞外多糖EPS-K1B3为壁材,研究微囊化香叶醇粉末的形成。对在pH值为5或pH值为7条件下制备的功能性乳液,针对革兰氏阳性菌(ATCC 33090)和革兰氏阴性菌(DSM682)菌株进行了抗菌活性评估。结果表明,与湿香叶醇乳液相比,香叶醇微胶囊在孵育30天内具有延长的抗菌效果,这可以证实喷雾干燥过程能够更长时间地保护包封的香叶醇。在pH值为5时,香叶醇微胶囊的抗菌效果最高。因此,除了目标细菌菌株外,pH值对香叶醇微胶囊功能特性的影响也值得关注。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/07ceba2d7fd6/life-13-01958-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/385cc02a67a9/life-13-01958-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/696ab3195c0d/life-13-01958-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/49baa4b1a000/life-13-01958-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/ff7458e33bc4/life-13-01958-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/07ceba2d7fd6/life-13-01958-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/385cc02a67a9/life-13-01958-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/696ab3195c0d/life-13-01958-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/49baa4b1a000/life-13-01958-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/ff7458e33bc4/life-13-01958-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3467/10608584/07ceba2d7fd6/life-13-01958-g005.jpg

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