Hughes Thomas, Harper Philip, Somani Bhaskar K
Department of Urology, South Warwickshire University Hospital NHS Foundation Trust, Warwick CV34 5BW, UK.
Department of Surgery, Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, UK.
Life (Basel). 2023 Oct 18;13(10):2077. doi: 10.3390/life13102077.
The management of benign prostatic obstruction (BPO) should involve a treatment algorithm that takes into account prostate size, and patient's symptoms and preference with the aim of helping with urinary symptoms and enhance quality of life. The diagnostic assessment for men with lower urinary tract symptoms (LUTS) should be comprehensive to help choose the best management strategy. Strategies from lifestyle modifications to medical treatment with alpha blockers and/or 5-alpha-reductase inhibitors to surgical procedures can all be used in the management algorithm. Surgical management ranges from transurethral resection of prostate (TURP) to minimally invasive surgical therapies (MIST) including laser therapies such as Holmium laser enucleation (HoLEP) and photoselective vaporisation (PVP), aquablation, Rezūm system, prostate artery embolisation (PAE), prostatic urethral lift (PUL), temporary implantable nitinol device (iTind) and Optilume BPH catheter system. BPO is a common urological condition that has a significant impact on quality of life and economic burden globally and is likely to become increasingly prevalent with an ageing population. Selecting the most appropriate treatment modality will depend on the individual patient preferences, availability of resources, cost, anatomical factors and the goals of treatment.
良性前列腺梗阻（BPO）的管理应采用一种治疗方案，该方案需考虑前列腺大小、患者症状及偏好，旨在缓解排尿症状并提高生活质量。对下尿路症状（LUTS）男性患者的诊断评估应全面，以帮助选择最佳管理策略。从生活方式改变到使用α受体阻滞剂和/或5-α还原酶抑制剂进行药物治疗，再到手术治疗等策略，均可用于管理方案中。手术管理范围从经尿道前列腺切除术（TURP）到微创外科治疗（MIST），包括激光治疗，如钬激光剜除术（HoLEP）和光选择性汽化术（PVP）、水刀切除术、Rezūm系统、前列腺动脉栓塞术（PAE）、前列腺尿道悬吊术（PUL）、临时植入镍钛诺装置（iTind）和Optilume BPH导管系统。BPO是一种常见的泌尿系统疾病，对全球生活质量和经济负担有重大影响，且随着人口老龄化可能会日益普遍。选择最合适的治疗方式将取决于个体患者的偏好、资源可用性、成本、解剖因素和治疗目标。
