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十二指肠转流术联合迷走神经切断术和胃窦切除术治疗重度或复发性反流性食管炎及狭窄:裂孔手术的替代方案

Duodenal diversion with vagotomy and antrectomy for severe or recurrent reflux oesophagitis and stricture: an alternative to operation at the hiatus.

作者信息

Washer G F, Gear M W, Dowling B L, Gillison E W, Royston C M, Spencer J

出版信息

Ann R Coll Surg Engl. 1986 Jul;68(4):222-6.

Abstract

In cases of mild symptomatic gastro-oesophageal reflux, standard antireflux surgery, such as fundoplication or the Angelchik prosthesis, produces satisfactory results. Duodenal diversion is recommended for use only in patients with severe oesophageal damage. This situation commonly arises where the gastro-oesophageal junction cannot be reduced into the abdomen, or where previous surgery has made reoperation at the hiatus difficult and hazardous. Fifty-seven patients with severe reflux oesophagitis have been treated by Roux-en-Y duodenal diversion and antrectomy. Thirty three patients had vagotomy in addition. Median follow-up after operation is 6.1 years. In 35 patients (61%), the technique was used as primary surgical treatment. These included 22 patients in a randomized trial of the method. Thirteen (23%) had previously had unsuccessful antireflux surgery. Nine (16%) had undergone previous operations for peptic ulcer or achalasia. There was no operative mortality. No patient in the series required stricture resection. Good or excellent overall results were achieved in 86% of patients. Eighteen of twenty seven patients with severe strictures required an average of three dilatations after operation before dysphagia was completely relieved. Heartburn was dramatically relieved and oesophagitis settled within an average period of 6 months. Poor or unsatisfactory overall results were observed in 8 (14%) patients. These included one tight fibrous stricture which required endoscopic intubation despite resolution of oesophagitis, and four patients who developed a stomal ulcer. No patients suffered from the dumping syndrome. Malignancy must be carefully excluded by biopsy in all cases of stricture.

摘要

对于轻度症状性胃食管反流病例,标准的抗反流手术,如胃底折叠术或安吉尔奇克假体植入术,可产生满意的效果。十二指肠转流术仅推荐用于食管严重受损的患者。这种情况通常发生在胃食管交界处无法还纳至腹腔时,或既往手术使得在裂孔处再次手术困难且危险时。57例重度反流性食管炎患者接受了Roux-en-Y十二指肠转流术和胃窦切除术治疗。另外33例患者还接受了迷走神经切断术。术后中位随访时间为6.1年。35例患者(61%)采用该技术作为初次手术治疗。其中包括22例该方法的随机试验患者。13例(23%)此前抗反流手术失败。9例(16%)既往接受过消化性溃疡或贲门失弛缓症手术。无手术死亡病例。该系列中无患者需要进行狭窄切除术。86%的患者取得了良好或极佳的总体效果。27例重度狭窄患者中有18例术后平均需要进行3次扩张才能完全缓解吞咽困难。烧心症状显著缓解,食管炎平均在6个月内得到缓解。8例(14%)患者总体效果较差或不满意。其中包括1例致密纤维性狭窄,尽管食管炎已缓解,但仍需要内镜插管,以及4例发生吻合口溃疡的患者。无患者出现倾倒综合征。在所有狭窄病例中,必须通过活检仔细排除恶性肿瘤。

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Surgical Management of Reflux Esophagitis.反流性食管炎的外科治疗
Ann Surg. 1961 Apr;153(4):555-62. doi: 10.1097/00000658-196104000-00019.
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GASTRO-OESOPHAGEAL REFLUX AFTER PARTIAL GASTRECTOMY.胃部分切除术后的胃食管反流
Br Med J. 1964 Nov 14;2(5419):1233-4. doi: 10.1136/bmj.2.5419.1233.
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Oesophageal stricture after partial gastrectomy.胃部分切除术后食管狭窄
Br J Surg. 1961 Nov;49:307-13. doi: 10.1002/bjs.18004921515.

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