Muhoza Pierre, Shah Monica P, Gao Hongjiang, Amponsa-Achiano Kwame, Quaye Pamela, Opare William, Okae Charlotte, Aboyinga Philip-Neri, Opare Kwadwo L, Wardle Melissa T, Wallace Aaron S
Global Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, GA 30329, USA.
Vaccines (Basel). 2023 Sep 23;11(10):1515. doi: 10.3390/vaccines11101515.
Understanding the drivers of coverage for vaccines offered in the second year of life (2YL) is a critical focus area for Ghana's life course approach to vaccination. This study characterizes the predictors of vaccine receipt for 2YL vaccines-meningococcal serogroup A conjugate vaccine (MACV) and the second dose of measles-containing vaccine (MCV2)-in Ghana.
1522 children aged 18-35 months were randomly sampled through household surveys in the Greater Accra Region (GAR), Northern Region (NR), and Volta Region (VR). The association between predictors and vaccination status was modeled using logistic regression with backwards elimination procedures. Predictors included child, caregiver, and household characteristics.
Coverage was high for infant vaccines (>85%) but lower for 2YL vaccines (ranging from 60.2% for MACV in GAR to 82.8% for MCV2 in VR). Predictors of vaccination status varied by region. Generally, older, first-born children, those living in rural settlements and those who received their recommended infant vaccines by their first birthday were the most likely to have received 2YL vaccines. Uptake was higher among those with older mothers and children whose caregivers were aware of the vaccination schedule.
Improving infant immunization uptake through increased community awareness and targeted strategies, such as parental reminders about vaccination visits, may improve 2YL vaccination coverage.
了解一岁至两岁儿童(2YL)疫苗接种覆盖率的驱动因素是加纳生命历程疫苗接种方法的关键重点领域。本研究描述了加纳一岁至两岁儿童疫苗(A群脑膜炎球菌结合疫苗(MACV)和第二剂含麻疹疫苗(MCV2))接种情况的预测因素。
通过对大阿克拉地区(GAR)、北部地区(NR)和沃尔特地区(VR)的家庭调查,随机抽取了1522名年龄在18 - 35个月的儿童。使用逻辑回归和向后消除程序对预测因素与疫苗接种状况之间的关联进行建模。预测因素包括儿童、照料者和家庭特征。
婴儿疫苗接种覆盖率较高(>85%),但一岁至两岁儿童疫苗接种覆盖率较低(从大阿克拉地区MACV的60.2%到沃尔特地区MCV2的82.8%不等)。疫苗接种状况的预测因素因地区而异。一般来说,年龄较大的头胎儿童、居住在农村地区的儿童以及在一岁生日前接种了推荐婴儿疫苗的儿童最有可能接种一岁至两岁儿童疫苗。母亲年龄较大的儿童以及照料者了解疫苗接种时间表的儿童接种率更高。
通过提高社区意识和采取有针对性的策略,如向家长提醒疫苗接种时间,提高婴儿免疫接种率,可能会提高一岁至两岁儿童疫苗接种覆盖率。