Demewoz Aynalem, Wubie Moges, Mengie Muluye Gebrie, Kassegn Esmelealem Mihretu, Jara Dubie, Aschale Abiot, Endalew Bekalu
1West Gojjam Zone Health Department, Jabitehnan District Health Office, Amhara Region, Finote Selam, Ethiopia.
2Department of Public Health, College of Medicine and Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Dose Response. 2023 Mar 10;21(1):15593258231164042. doi: 10.1177/15593258231164042. eCollection 2023 Jan-Mar.
Herd immunity against measles is essential to interrupt measles transmission, and this can only be attained by reaching at least 95% coverage for each of the 2 doses of measles vaccine provided in infancy and early childhood age group. It is important to provide everyone with 2 doses of the measles vaccine in order to effectively safeguard the population. Despite this, little is known about the second dosage of the measles vaccine utilization status and the factors that affect it. Therefore, this study aimed to assess second dose of measles vaccination utilization and its associated factors among children aged 24-35 months in Jabitehnan district, 2020.
A community-based cross-sectional study design was conducted at Jabitehnan District, Northwest Ethiopia, from September 1st, 2020 to October 1st, 2020. Systematic random sampling technique was used to select 845 mothers/caregivers who had children aged 24-35 months. Both bi-variable and multivariable logistic regression was fitted to identify the determinant factors of second dose measles vaccination utilization. Finally, the statistical significant variables were declared by using 95% CI and value less than .05 in the multivariable logistic regression analysis. The Hosmer and Lemeshow test was used to check the model's fit to the data, and the variance inflation factor was used to assess multi-collinearity.
The overall second dose of measles vaccination utilization was 48.1%, (95% CI: 44.7-51.6). Mothers with primary school education (AOR = 1.91, 95% CI: 1.15-3.17), information about MCV2 (AOR = 6.53, 95% CI: 4.22-10.08), distance from vaccination site (AOR = 3.56, 95% CI: 2.46-5.14), knowledge about immunization (AOR = 1.935, 95% CI: 1.29-2.90), and favorable attitude about immunization (AOR = 5.19, 95% CI: 3.25-8.29) were significantly associated factors with second dose of measles vaccination utilization.
Second dose measles vaccination utilization in the district was lower than the national target. Maternal education, distances from vaccination site, information about MCV2, and knowledge about immunization were significantly associated variables with second dose measles vaccination utilization. Therefore, in order to increase the utilization of the second dose of the measles vaccine, improved health education and service expansion to difficult-to-reach areas are required.
麻疹群体免疫对于阻断麻疹传播至关重要,而这只有在婴幼儿及儿童早期年龄组中两剂麻疹疫苗的接种覆盖率均至少达到95%时才能实现。为有效保护人群,为每个人接种两剂麻疹疫苗很重要。尽管如此,对于麻疹疫苗第二剂的使用情况及其影响因素却知之甚少。因此,本研究旨在评估2020年贾比特南地区24至35个月龄儿童中麻疹疫苗第二剂的接种情况及其相关因素。
2020年9月1日至10月1日在埃塞俄比亚西北部的贾比特南地区开展了一项基于社区的横断面研究设计。采用系统随机抽样技术选取了845名有24至35个月龄儿童的母亲/照料者。运用双变量和多变量逻辑回归来确定麻疹疫苗第二剂接种的决定因素。最后,在多变量逻辑回归分析中,使用95%置信区间和小于0.05的值来确定具有统计学意义的变量。采用Hosmer和Lemeshow检验来检验模型对数据的拟合情况,并使用方差膨胀因子来评估多重共线性。
麻疹疫苗第二剂的总体接种率为48.1%,(95%置信区间:44.7 - 51.6)。接受小学教育的母亲(调整后比值比 = 1.91,95%置信区间:1.15 - 3.17)、关于麻疹风疹联合疫苗第二剂(MCV2)的信息(调整后比值比 = 6.53,95%置信区间:4.22 - 10.08)、与接种地点的距离(调整后比值比 = 3.56,95%置信区间:2.46 - 5.14)、免疫知识(调整后比值比 = 1.935,95%置信区间:1.29 - 2.90)以及对免疫的积极态度(调整后比值比 = 5.19,95%置信区间:3.25 - 8.29)是与麻疹疫苗第二剂接种显著相关的因素。
该地区麻疹疫苗第二剂的接种率低于国家目标。母亲教育程度、与接种地点的距离、关于MCV2的信息以及免疫知识是与麻疹疫苗第二剂接种显著相关的变量。因此,为提高麻疹疫苗第二剂的接种率,需要加强健康教育并将服务扩展到难以到达的地区。