Colomé-Ceballos Lara, Clua-Espuny Josep Lluís, Ceballos-García Concepción, Clua-Queralt Josep, Pla-Farnós Maria Jesús, Fernández-Sáez José
Sexual and Reproductive Attention, SAP Terres de l'Ebre, Catalonian Health Institute, 43500 Catalonia, Spain.
Gynaecology Department, Hospital Verge de la Cinta de Tortosa, Catalonian Health Institute, 43500 Catalonia, Spain.
Vaccines (Basel). 2023 Sep 28;11(10):1536. doi: 10.3390/vaccines11101536.
HPV vaccination coverage rates can vary depending on several factors. The main objective of this study is to identify possible independent prognostic factors that have an impact on HPV vaccination in a rural community, specifically related to sexual and reproductive health. A case-control, retrospective, community-based study was carried out on women aged 15 to 40 in the primary health centers of Southern Catalonia's Terres de l'Ebre region, Spain, from 1 January 2020 to 31 December 2022. A random sample of 520 women with an average age of 29.3 (SD 7.8) years old was included in the study. Independent prognostic factors: age OR 0.680 (95% CI: 0.635-0.729, < 0.001), immigrant origin OR 0.215 (95% CI: 0.109-0.422, < 0.001), and HPV PCR OR 7.402 (95% CI: 2.504-21.880, < 0.001). The variables that showed a barrier effect for HPV vaccination were age (OR 0.680, 95% CI 0.635-0.729, < 0.001), and immigrant origin (OR 0.215, 95% CI 0.109-0.422, < 0.001). The variable that showed a facilitating effect for HPV vaccination was HPV PCR (OR 7.402, 95% CI 2.504-21.880, < 0.001).
人乳头瘤病毒（HPV）疫苗接种覆盖率可能因多种因素而异。本研究的主要目的是确定可能对农村社区HPV疫苗接种产生影响的独立预后因素，特别是与性健康和生殖健康相关的因素。2020年1月1日至2022年12月31日，在西班牙加泰罗尼亚南部埃布罗河畔地区的初级卫生中心，对15至40岁的女性进行了一项病例对照、回顾性、基于社区的研究。该研究纳入了520名平均年龄为29.3岁（标准差7.8岁）的女性随机样本。独立预后因素：年龄，优势比（OR）为0.680（95%置信区间：0.635 - 0.729，P < 0.001）；移民身份，OR为0.215（95%置信区间：0.109 - 0.422，P < 0.001）；HPV聚合酶链反应（PCR）检测结果，OR为7.402（95%置信区间：2.504 - 21.880，P < 0.001）。对HPV疫苗接种显示出阻碍作用的变量是年龄（OR 0.680，95%置信区间0.635 - 0.729，P < 0.001）和移民身份（OR 0.215，95%置信区间0.109 - 0.422，P < 0.001）。对HPV疫苗接种显示出促进作用的变量是HPV PCR检测结果（OR 7.402，95%置信区间2.504 - 21.880，P < 0.001）。
