Colomé-Ceballos Lara, Clua-Espuny Josep Lluís, Fernández-Sáez José, Ceballos-García Concepción, Andrés-Cubells Natàlia, Pla-Farnós Maria Jesús
Sexual and Reproductive Attention, SAP Terres de l'Ebre, Catalonian Health Institute, 43500 Tortosa, Spain.
Gynaecology Department, Hospital Verge de la Cinta de Tortosa, Catalonian Health Institute, 43500 Tortosa, Spain.
Vaccines (Basel). 2022 Aug 7;10(8):1274. doi: 10.3390/vaccines10081274.
In order to reduce the incidence and mortality rate of cervical cancer, the World Health Organization (WHO) declared the Global Strategy Goal for 2030, advocating for reaching a vaccination coverage rate of >90% against human papillomavirus for girls by the age of 15 years. The main objectives of this study were (1) to determine the papillomavirus vaccination coverage among women 15−40 years old and (2) to identify the at-risk subgroups and possible barriers to achieving WHO’s 2030 goal. Multicentre, observational, retrospective, and community-based cohort studies were conducted on women from a rural area in southern Catalonia until 31 December 2021. A total of 23,136 women were included, with a mean age of 26.6 (SD = 5.6) years. The average dose number was 1.7 (SD = 0.7). The results showed overall vaccination coverage of 17.4% among the target women. This coverage was unequal across regions (16.6−24.5%, p < 0.001), primary healthcare teams (15.5−24.3%, p < 0.001), and age groups (56.7% (15−19-year-olds) vs. 3.8% (35−40-year-olds), p < 0.001), related to accessibility to vaccination and economic−geographical indicators. Clinical practice guidelines on screening individuals at risk in terms of vaccination access and public vaccination protocols should be implemented in order to improve the vaccination coverage rate.
为降低宫颈癌的发病率和死亡率，世界卫生组织（WHO）宣布了2030年全球战略目标，倡导15岁女孩的人乳头瘤病毒疫苗接种覆盖率达到90%以上。本研究的主要目的是：（1）确定15至40岁女性的乳头瘤病毒疫苗接种覆盖率；（2）确定高危亚组以及实现WHO 2030年目标的可能障碍。对加泰罗尼亚南部农村地区的女性进行了多中心、观察性、回顾性和基于社区的队列研究，直至2021年12月31日。共纳入23136名女性，平均年龄为26.6（标准差=5.6）岁。平均接种剂数为1.7（标准差=0.7）。结果显示，目标女性的总体疫苗接种覆盖率为17.4%。不同地区（1,6.6−24.5%，p<0.001）、基层医疗团队（15.5−24.3%，p<0.001）和年龄组（15至19岁组为56.7%，35至40岁组为3.8%，p<0.001）的覆盖率不平等，这与疫苗接种的可及性和经济地理指标有关。应实施关于筛查接种风险个体的临床实践指南以及公共疫苗接种方案，以提高疫苗接种覆盖率。
