Iqbal Muhammad Shahid, Khan Salah-Ud-Din, Qamer Shafqat, Vohra Saeed
Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam bin Abdulaziz University, Al-kharj 11942, Saudi Arabia.
Department of Biochemistry, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11432, Saudi Arabia.
Vaccines (Basel). 2023 Oct 1;11(10):1556. doi: 10.3390/vaccines11101556.
The current systematic review presents COVID-19 vaccine hesitancy among parents for their children in Middle Eastern countries. Moreover, the vaccine acceptance rate of parents from the Middle East and the factors effecting the acceptance rate were reviewed and summarized. For this systematic review, basic electronic academic databases (Scopus, Science Direct, ProQuest, Web of Science and PubMed) were used for the search, along with a manual search on Google Scholar. This systematic review was conducted by following the "Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)" guidelines. Moreover, utilizing the framework of the PECO-S (Population Exposure Comparison Outcome Study design), various observational studies were recruited for this review. Out of 2123 studies, 25 studies meeting the inclusion criteria were included in the current review. All of the included studies were about parental vaccine hesitancy for COVID-19 in Middle Eastern countries and published during 2020-2022. Overall, 25 research papers comprising 10 different Middle Eastern countries with 33,558 parents were included. The average age of parents was 39.13 (range: 18-70) years, while the mean age of children was 7.95 (range: 0-18) years. The overall hesitancy rate was 44.2% with a SD of ± 19.7. The included studies presented enhanced COVID-19 vaccine hesitancy among parents in Middle Eastern countries. The lower vaccine acceptance rate among parents was mainly because of a fear of the potential side effects. Furthermore, the lack of information regarding vaccine safety and efficacy, the fear of unreported side effects and concerns about the authenticity of vaccine development and preparation were the predictors of parental COVID-19 vaccine hesitancy among Middle Eastern countries.
本系统评价介绍了中东国家父母对其子女接种新冠疫苗的犹豫情况。此外，还对中东地区父母的疫苗接受率以及影响接受率的因素进行了综述和总结。对于本系统评价，使用了基本的电子学术数据库（Scopus、Science Direct、ProQuest、Web of Science和PubMed）进行检索，并在谷歌学术上进行了手动检索。本系统评价遵循“系统评价和Meta分析的首选报告项目（PRISMA）”指南进行。此外，利用PECO-S（人群、暴露、比较、结局、研究设计）框架，为本评价纳入了各种观察性研究。在2123项研究中，有25项符合纳入标准的研究被纳入本次评价。所有纳入的研究均是关于中东国家父母对新冠疫苗的犹豫情况，且发表于2020年至2022年期间。总体而言，纳入了25篇研究论文，涉及10个不同的中东国家的33558名父母。父母的平均年龄为39.13岁（范围：18 - 70岁），而儿童的平均年龄为7.95岁（范围：0 - 18岁）。总体犹豫率为44.2%，标准差为±19.7。纳入的研究表明中东国家父母对新冠疫苗的犹豫情绪有所增强。父母中较低的疫苗接受率主要是因为担心潜在的副作用。此外，缺乏关于疫苗安全性和有效性的信息、对未报告副作用的恐惧以及对疫苗研发和制备真实性的担忧是中东国家父母对新冠疫苗犹豫的预测因素。
