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Role of Postnatal Corticosteroids in the Treatment or Prevention of Bronchopulmonary Dysplasia.

作者信息

Bulbul Ali, Bacak Tolga, Avsar Hasan

机构信息

Department of Pediatrics, Division of Neonatology, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.

出版信息

Sisli Etfal Hastan Tip Bul. 2023 Jun 20;57(2):171-181. doi: 10.14744/SEMB.2023.80688. eCollection 2023.


DOI:10.14744/SEMB.2023.80688
PMID:37899802
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10600625/
Abstract

As the frequency of viable low birth weight preterm babies increases, bronchopulmonary dysplasia (BPD), one of the most important morbidities in these babies, also increases. Using postnatal steroids to reduce the development of BPD has not been fully enlightened. Besides all prevention strategies for reducing the development of BPD, it is known that steroid therapy used in the 1 week of life could induce negative neuromotor development according to current data. It may be recommended to administer low-dose dexamethasone between 8 and 49 days in infants dependent on mechanical ventilators in the postnatal period. It is seen that the use of hydrocortisone in the early period does not cause negative neuromotor development, but it cannot prevent the development of BPD as much as dexamethasone. All intensive care units must have their steroid protocol for BPD and use steroids in cases when the BPD development scale score is >60-65% and should have a goal of trying to keep the cumulative dose at the lowest level.

摘要

相似文献

[1]
Role of Postnatal Corticosteroids in the Treatment or Prevention of Bronchopulmonary Dysplasia.

Sisli Etfal Hastan Tip Bul. 2023-6-20

[2]
Postnatal corticosteroids to prevent or treat bronchopulmonary dysplasia in preterm infants.

Paediatr Child Health. 2020-8

[3]
Early (< 8 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants.

Cochrane Database Syst Rev. 2017-10-24

[4]
Inhaled versus systemic corticosteroids for preventing bronchopulmonary dysplasia in ventilated very low birth weight preterm neonates.

Cochrane Database Syst Rev. 2017-10-17

[5]
[The use of postnatal corticosteroid therapy in premature infants to prevent or treat bronchopulmonary dysplasia: current situation and recommendations].

Arch Pediatr. 2010-10

[6]
Late (> 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants.

Cochrane Database Syst Rev. 2017-10-24

[7]
Inhalation or instillation of steroids for the prevention of bronchopulmonary dysplasia.

Neonatology. 2015

[8]
[Glucocorticoide therapy in premature infants: French practices in 2006].

Arch Pediatr. 2009-7

[9]
Late (≥ 7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants.

Cochrane Database Syst Rev. 2017-8-24

[10]
The effect of postnatal corticosteroids on growth parameters in infants with bronchopulmonary dysplasia.

J Perinat Med. 2021-11-25

本文引用的文献

[1]
Factors associated with successful extubation following the first course of systemic dexamethasone in ventilator-dependent preterm infants with or at risk of developing bronchopulmonary dysplasia.

Pediatr Pulmonol. 2022-4

[2]
Early (&lt; 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants.

Cochrane Database Syst Rev. 2021-10-21

[3]
An Update on the Prevention and Management of Bronchopulmonary Dysplasia.

Pediatric Health Med Ther. 2021-8-11

[4]
Effect of Systemic Hydrocortisone Initiated 7 to 14 Days After Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial.

JAMA. 2021-7-27

[5]
Life-threatening bronchopulmonary dysplasia: a British Paediatric Surveillance Unit Study.

Arch Dis Child Fetal Neonatal Ed. 2022-1

[6]
Effectiveness and safety of repeat dexamethasone for bronchopulmonary dysplasia.

J Perinatol. 2021-8

[7]
The effect of postnatal corticosteroids on growth parameters in infants with bronchopulmonary dysplasia.

J Perinat Med. 2021-11-25

[8]
Postnatal steroid management in preterm infants with evolving bronchopulmonary dysplasia.

J Perinatol. 2021-8

[9]
Postnatal Corticosteroids to Prevent or Treat Bronchopulmonary Dysplasia.

Neonatology. 2021

[10]
Intra-tracheal surfactant/budesonide versus surfactant alone: Comparison of two consecutive cohorts of extremely preterm infants.

Pediatr Pulmonol. 2021-7

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