Davis N, Bossung-Sweeney L, Peterson D R
Aust Paediatr J. 1986;22 Suppl 1:29-32.
A unique opportunity to study proven infant apnoea (PIA) and Sudden Infant Death Syndrome (SIDS) occurrences epidemiologically in 12 Counties in north-western Washington State during the same time period during which 180,017 live births were recorded revealed markedly dissimilar distribution patterns. The overall incidence of SIDS exceeded that of PIA by a factor of 3. Five PIA babies subsequently succumbed to SIDS. Statistical analysis reveals that these five events cannot be explained as random coincidences; they represent 3% of 163 PIA cases but only 1% of 503 SIDS occurrences. Infant apnoea is an infrequent precursor of SIDS. These results do not support the view that SIDS and infant apnoea are related conditions caused by a common underlying disorder. Aetiological models other than infant apnoea must be devised if the momentum of SIDS research is to be sustained.
在华盛顿州西北部12个县对确诊的婴儿呼吸暂停（PIA）和婴儿猝死综合征（SIDS）发病情况进行同期流行病学研究的独特机会，在记录了180,017例活产的同一时期内，揭示了明显不同的分布模式。SIDS的总体发病率超过PIA发病率3倍。5名PIA婴儿随后死于SIDS。统计分析表明，这5起事件不能解释为随机巧合；它们占163例PIA病例的3%，但仅占503例SIDS病例的1%。婴儿呼吸暂停是SIDS罕见的先兆。这些结果不支持SIDS和婴儿呼吸暂停是由共同潜在疾病引起的相关病症这一观点。如果要保持SIDS研究的势头，就必须设计出除婴儿呼吸暂停之外的病因模型。
