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早期肾病患者肾脏形态与体型组成的研究

Investigation of Kidney Morphology and Somatotype Components in Early-Stage Kidney Patients.

作者信息

Ulubaba Hilal Er, Cinarli Fahri Safa, Ciftci Rukiye, Ulutas Ozkan

机构信息

Department of Radiology, Yesilyurt Hasan Calik State Hospital, Malatya, Türkiye.

Department of Movement and Training Science, Inonu University, Malatya, Türkiye.

出版信息

Sisli Etfal Hastan Tip Bul. 2023 Sep 29;57(3):353-358. doi: 10.14744/SEMB.2023.08365. eCollection 2023.

DOI:10.14744/SEMB.2023.08365
PMID:37900334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10600599/
Abstract

OBJECTIVES

The aim of this study is to examine the kidney morphology and somatotype components of adult patients with early-stage chronic kidney disease (CKD).

METHODS

The sample consisted of 46 individuals with early-stage CKD (26 men and 20 women, mean age=45.92±16.53 years). The pathological subjects were compared with a control group consisting of 46 healthy subjects (28 men and 18 women, mean age=41.96±11.48 years). The Heath-Carter method was used to determine somatotype components. Abdominal computed tomography (CT) of patients with Stage 2 CKD and healthy volunteers taken within the past 3 months was scanned to determine kidney morphology. Kidney measurements were performed on CTs (length, width, depth, and volume of kidney).

RESULTS

Kidney patients (mean somatotype: 6.33-5.37-0.6) were less ectomorphic and more endomorphic than the controls (mean somatotype: 4.35-4.40-3.02). Moderate effect size (ES) was found in endomorphy (ES=0.87; p=0.035) and ectomorphy (ES=1.08; p=0.012) between groups. No significant difference was observed in the kidney morphology (ES=0.04-0.19; p>0.05).

CONCLUSION

In the early-stage CKD, kidney morphology may not be the distinguishing factor. On the other hand, patients differed significantly in terms of endomorph components. Being overweight can also be one of the negative findings for kidney disease. Somatotype classification could be a suitable tool for monitoring kidney disease.

摘要

目的

本研究旨在检查成年早期慢性肾脏病(CKD)患者的肾脏形态和体型组成部分。

方法

样本包括46例早期CKD患者(26名男性和20名女性,平均年龄 = 45.92±16.53岁)。将这些病理受试者与由46名健康受试者组成的对照组(28名男性和18名女性,平均年龄 = 41.96±11.48岁)进行比较。采用希思 - 卡特法确定体型组成部分。对过去3个月内接受检查的2期CKD患者和健康志愿者进行腹部计算机断层扫描(CT),以确定肾脏形态。在CT上进行肾脏测量(肾脏的长度、宽度、深度和体积)。

结果

肾病患者(平均体型:6.33 - 5.37 - 0.6)比对照组(平均体型:4.35 - 4.40 - 3.02)的外胚层体型特征更少,内胚层体型特征更多。两组在内胚层体型特征(效应量[ES]=0.87;p = 0.035)和外胚层体型特征(ES = 1.08;p = 0.012)方面存在中等效应量。在肾脏形态方面未观察到显著差异(ES = 0.04 - 0.19;p>0.05)。

结论

在早期CKD中,肾脏形态可能不是区分因素。另一方面,患者在内胚层组成部分方面存在显著差异。超重也可能是肾病的负面表现之一。体型分类可能是监测肾病的合适工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f905/10600599/595c5b46c5e2/SEMB-57-353-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f905/10600599/4cbefefb4a0e/SEMB-57-353-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f905/10600599/f50d53a9b613/SEMB-57-353-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f905/10600599/595c5b46c5e2/SEMB-57-353-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f905/10600599/4cbefefb4a0e/SEMB-57-353-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f905/10600599/f50d53a9b613/SEMB-57-353-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f905/10600599/595c5b46c5e2/SEMB-57-353-g003.jpg

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