Bernard Mathilde, Samargandi Ramy
Orthopedic Surgery Department, Centre Hospitalier Régional Universitaire (CHRU) de Tours, Tours, FRA.
Orthopedic Surgery Department, Faculty of Medicine, University of Jeddah, Jeddah, SAU.
Cureus. 2023 Sep 26;15(9):e45974. doi: 10.7759/cureus.45974. eCollection 2023 Sep.
Mesenchymal chondrosarcomas are extremely rare and aggressive tumors that primarily affect patients between the ages of 20 and 30. These neoplasms are typically found in the lower limbs and cranial region. Their occurrence within soft tissues is exceedingly rare, and the initial presentation often includes immediate metastatic dissemination. Given the extraordinarily low prevalence of extraskeletal mesenchymal chondrosarcoma, treatment approaches remain non-standardized. Surgical resection combined with neoadjuvant chemotherapy or radiotherapy is the most commonly favored strategy by medical teams. In this case report, we present the case of a 72-year-old patient with no specific medical history, who presented with a non-metastatic extraskeletal mesenchymal chondrosarcoma located in the popliteal fossa. The therapeutic intervention encompassed surgical resection followed by adjuvant radiotherapy. After 18 months of follow-up period, there was no evidence of local recurrence or distant metastases. The disparity between the patient's clinical characteristics and the existing medical literature may provide new insights into understanding this neoplastic entity.
间叶性软骨肉瘤是极其罕见且侵袭性强的肿瘤，主要影响20至30岁的患者。这些肿瘤通常发生在下肢和颅骨区域。它们在软组织中的出现极为罕见，最初表现往往包括即刻发生转移扩散。鉴于骨外间叶性软骨肉瘤的发病率极低，治疗方法仍未标准化。手术切除联合新辅助化疗或放疗是医疗团队最常用的治疗策略。在本病例报告中，我们呈现了一名72岁、无特殊病史的患者，其患有位于腘窝的非转移性骨外间叶性软骨肉瘤。治疗干预包括手术切除，随后进行辅助放疗。经过18个月的随访期，没有局部复发或远处转移的迹象。该患者的临床特征与现有医学文献之间的差异可能为理解这种肿瘤实体提供新的见解。
