Channaoui Aniss, Dubus Michèle, Mathieu Frédéric, Noirhomme Séverine, Fontaine Raphaël
Cardiac Surgery Department, Centre Hospitalier Régional Sambre et Meuse, Namur, BEL.
Cardiology Department, Centre Hospitalier Régional Sambre et Meuse, Namur, BEL.
Cureus. 2023 Sep 27;15(9):e46045. doi: 10.7759/cureus.46045. eCollection 2023 Sep.
An immunocompetent 82-year-old woman developed endocarditis caused by an atypical organism called Achromobacter xylosoxidans, after a first valvular surgery. The intravenous antibiotic therapy with ceftazidime - 2 g every 8 hours during five weeks - a key part of the treatment, induced agranulocytosis as an adverse event. Cross-reactivity between antibiotics was suspected. Finally, the patient's cure was the result of a coordinated effort between medical and surgical professionals. Postoperative follow-up is six years.
一名免疫功能正常的82岁女性在首次进行瓣膜手术后，感染了一种名为木糖氧化无色杆菌的非典型病原体，引发了心内膜炎。在为期五周的治疗中，关键部分是每8小时静脉注射2克头孢他啶，这一抗生素治疗引发了粒细胞缺乏症这一不良事件。怀疑抗生素之间存在交叉反应。最终，患者的治愈是医疗和外科专业人员共同努力的结果。术后随访六年。
