Department of Medicine, Division of Infectious Diseases, Virginia Commonwealth University Medical Center;
Can J Infect Dis Med Microbiol. 2011 Fall;22(3):e17-20. doi: 10.1155/2011/527412.
Endocarditis due to Achromobacter species is a rare, yet serious, endovascular infection. Achromobacter species infective endocarditis is associated with underlying immunodeficiencies or prosthetic heart valves and devices. A case of prosthetic pulmonary valve endocarditis secondary to Achromobacter xylosoxidans subspecies denitrificans is described in the present report. This life-threatening infection was successfully treated with combined valve replacement and prolonged antibiotic therapy. A Medline/PubMed literature review of Achromobacter endocarditis was also performed. Achromobacter species are an uncommon, yet important, cause of nosocomial endocarditis. Given the significant associated morbidity and mortality, along with a high degree of intrinsic antibiotic resistance, Achromobacter species infective endocarditis remains a clinical treatment challenge.
阿氏菌属引起的心内膜炎是一种罕见但严重的血管内感染。阿氏菌属感染性心内膜炎与潜在的免疫缺陷或人工心脏瓣膜和装置有关。本报告描述了一例继发于氧化木醋酸杆菌亚种脱硝亚种的人工肺动脉瓣心内膜炎。这种危及生命的感染通过联合瓣膜置换和延长抗生素治疗成功治愈。还对阿氏菌属心内膜炎的 Medline/PubMed 文献进行了回顾。阿氏菌属是医院获得性心内膜炎的一种不常见但重要的病因。鉴于其严重的相关发病率和死亡率,以及高度的固有抗生素耐药性,阿氏菌属感染性心内膜炎仍然是临床治疗的挑战。