Xiao Qi-Fan, Li Jie, Tang Bin, Zhu Yu-Qing
Department of International General Practice, China-Japan Friendship Hospital, Beijing 100029, China.
Department of General Practice, Xinggu Street Community Health Service Center, Beijing 101200, China.
World J Clin Cases. 2023 Oct 6;11(28):6902-6907. doi: 10.12998/wjcc.v11.i28.6902.
Testicular mixed germ cell tumors (TMGCTs) are rare malignant tumors that are more common in men aged 20-40 years. TMGCTs comprise two or more types of germ cell tumors that primarily affect the testis. Their onset is undetectable; thus, early diagnosis is challenging. However, early recognition and diagnosis substantially improve patient prognosis.
We evaluated a rare case of TMGCT in a male patient presenting with recurrent fever and left supraclavicular lymphadenectasis instead of testicular enlargement and pain, which may easily lead to misdiagnosis. We report the clinical signs and symptoms, histopathological characteristics, and immunohistochemical results of this case of malignant TMGCT.
Our case, which was typical with multiple components, along with a literature review, may serve as a basis for early diagnosis.
睾丸混合性生殖细胞肿瘤（TMGCTs）是罕见的恶性肿瘤，在20至40岁男性中更为常见。TMGCTs由两种或更多种主要影响睾丸的生殖细胞肿瘤组成。其发病难以察觉，因此早期诊断具有挑战性。然而，早期识别和诊断可显著改善患者预后。
我们评估了一例罕见的TMGCT男性患者，该患者表现为反复发热和左锁骨上淋巴结肿大，而非睾丸肿大和疼痛，这可能容易导致误诊。我们报告了该例恶性TMGCT的临床体征和症状、组织病理学特征及免疫组化结果。
我们这例具有多种成分的典型病例，结合文献复习，可为早期诊断提供依据。
