Wang Jiang-Long, Wu Xi-Wen, Wang Sheng-Nan, Liu Xuan, Xiao Bing, Wang Yu, Yu Jing
The First Operating Room, The First Hospital of Jilin University, Changchun 130000, Jilin Province, China.
Department of Neurology, The First Hospital of Jilin University, Changchun 130000, Jilin Province, China.
World J Clin Cases. 2023 Oct 6;11(28):6680-6687. doi: 10.12998/wjcc.v11.i28.6680.
At present, many studies have reported the risk factors for postoperative intracranial reinfection, including age, sex, time to surgery, duration of postoperative catheterization, emergency procedures, type of disease and cerebrospinal fluid leakage, but the academic community has not reached a unified conclusion.
To find factors influencing the surveillance of re-emerging intracranial infections in elective neurosurgical patients.
Ninety-four patients who underwent elective craniotomy from January 1, 2015 to December 31, 2022 in the Department of Neurosurgery, First Hospital of Jilin University, were included in this study. Of those, 45 patients were enrolled in the infection group, and 49 were enrolled in the control group. The clinical data of the patients were collected and divided into three categories, including preoperative baseline conditions, intraoperative characteristics and postoperative infection prevention. The data were analyzed using SPSS 26.0 software.
There were 23 males and 22 females in the infection group with a mean age of 52.8 ± 15.1 years and 17 males and 32 females in the control group with a mean age of 48.9 ± 15.2 years. The univariate analysis showed that the infection group had higher systolic blood pressures and postoperative temperatures, fewer patients who underwent a supratentorial craniotomy, more patients with a history of hypertension and higher initial postoperative white blood cell counts than the control group, with statistically significant differences ( < 0.05). The multifactorial logistic regression analysis showed that a history of hypertension and a high postoperative body temperature were independent risk factors for postoperative infection in neurosurgical patients.
The results obtained in this study indicated that a history of hypertension and a high postoperative body temperature were independent risk factors for postoperative neurological symptoms.
目前，许多研究报道了术后颅内再感染的危险因素，包括年龄、性别、手术时间、术后置管时间、急诊手术、疾病类型和脑脊液漏等，但学术界尚未达成统一结论。
寻找影响择期神经外科手术患者颅内再感染监测的因素。
纳入2015年1月1日至2022年12月31日在吉林大学第一医院神经外科行择期开颅手术的94例患者。其中，45例患者纳入感染组，49例患者纳入对照组。收集患者的临床资料，并分为术前基线情况、术中特征和术后感染预防三类。采用SPSS 26.0软件进行数据分析。
感染组男23例，女22例，平均年龄52.8±15.1岁；对照组男17例，女32例，平均年龄48.9±15.2岁。单因素分析显示，感染组的收缩压和术后体温较高，幕上开颅手术的患者较少，有高血压病史的患者较多，术后初始白细胞计数高于对照组，差异有统计学意义（<0.05）。多因素logistic回归分析显示，高血压病史和术后体温高是神经外科手术患者术后感染的独立危险因素。
本研究结果表明，高血压病史和术后体温高是术后神经症状的独立危险因素。
