Division of Applied Life Science (BK21 Four Program), Plant Molecular Biology and Biotechnology Research Center, Gyeongsang National University, Jinju, Republic of Korea.
Plant Signal Behav. 2023 Dec 31;18(1):2270835. doi: 10.1080/15592324.2023.2270835. Epub 2023 Oct 30.
Quercetin is a flavonol belonging to the flavonoid group of polyphenols. Quercetin is reported to have a variety of biological functions, including antioxidant, pigment, auxin transport inhibitor and root nodulation factor. Additionally, quercetin is known to be involved in bacterial pathogen resistance in through the transcriptional increase of () genes. However, the molecular mechanisms underlying how quercetin promotes pathogen resistance remain elusive. In this study, we showed that the transcriptional increases of genes were achieved by the monomerization and nuclear translocation of nonexpressor of pathogenesis-related proteins 1 (NPR1). Interestingly, salicylic acid (SA) was approximately 2-fold accumulated by the treatment with quercetin. Furthermore, we showed that the increase of SA biosynthesis by quercetin was induced by the transcriptional increases of typical SA biosynthesis-related genes. In conclusion, this study strongly suggests that quercetin induces bacterial pathogen resistance through the increase of SA biosynthesis in .
槲皮素是一种属于类黄酮多酚的类黄酮醇。槲皮素据报道具有多种生物功能，包括抗氧化剂、色素、生长素运输抑制剂和根瘤因子。此外，已知槲皮素通过转录增加（）基因参与细菌病原体的抗性。然而，槲皮素促进病原体抗性的分子机制仍不清楚。在这项研究中，我们表明基因的转录增加是通过非致病性相关蛋白 1（NPR1）的单体化和核易位来实现的。有趣的是，用槲皮素处理可使水杨酸（SA）积累约 2 倍。此外，我们表明，槲皮素通过典型的 SA 生物合成相关基因的转录增加诱导 SA 生物合成的增加。总之，本研究强烈表明，槲皮素通过增加中的 SA 生物合成诱导细菌病原体的抗性。
