Plant Acquired Immunity Research Unit, RIKEN Advanced Science Institute, Wako 351-0198, Japan.
Department of Bioscience and Biotechnology, Fukui Prefectural University, Fukui 910-1195, Japan.
Int J Mol Sci. 2023 May 20;24(10):9037. doi: 10.3390/ijms24109037.
Systemic acquired resistance (SAR) is a potent innate immunity system in plants that is induced through the salicylic acid (SA)-mediated signaling pathway. Here, we characterized 3-chloro-1-methyl-1-pyrazole-5-carboxylic acid (CMPA) as an effective SAR inducer in . The soil drench application of CMPA enhanced a broad range of disease resistance against the bacterial pathogen and fungal pathogens and in , whereas CMPA did not show antibacterial activity. Foliar spraying with CMPA induced the expression of SA-responsible genes such as , and . The effects of CMPA on resistance against the bacterial pathogen and the expression of genes were observed in the SA biosynthesis mutant, however, while they were not observed in the SA-receptor-deficient mutant. Thus, these findings indicate that CMPA induces SAR by triggering the downstream signaling of SA biosynthesis in the SA-mediated signaling pathway.
系统获得性抗性 (SAR) 是植物中一种强大的先天免疫系统，通过水杨酸 (SA) 介导的信号通路诱导。在这里，我们将 3-氯-1-甲基-1-吡唑-5-羧酸 (CMPA) 鉴定为 的有效 SAR 诱导剂。CMPA 的土壤浇灌应用增强了对细菌病原体 和真菌病原体 和 的广泛的抗病性，而 CMPA 没有表现出抗菌活性。叶面喷施 CMPA 诱导了 SA 负责基因的表达，如 、 和 。在 SA 生物合成突变体中观察到 CMPA 对抵抗细菌病原体和 基因表达的影响，但在 SA 受体缺陷型 突变体中没有观察到。因此，这些发现表明 CMPA 通过触发 SA 介导的信号通路中 SA 生物合成的下游信号转导来诱导 SAR。
