Department of Comprehensive Dentistry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr., MSC 7914, San Antonio, TX 78229-3900, USA.
Department of Comprehensive Dentistry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr., MSC 7914, San Antonio, TX 78229-3900, USA.
Dent Mater. 2024 Jan;40(1):59-65. doi: 10.1016/j.dental.2023.10.024. Epub 2023 Oct 28.
To determine the effects of using K18-methyl methacrylate (K18-MMA) and K18-Filler on composite cure, esthetic, mechanical, polymerization shrinkage, and antimicrobial properties.
K18-MMA (0-20% w/w) was used to replace TEGDMA in a 70:30 Bis-GMA:TEGDMA composite filled to 70% w/w with barium glass or K18-Filler. Composite degree of cure (Rockwell hardness and near Infrared FTIR), hydrophilicity (contact angle measurements), translucency (transparency parameter measurements, TP), mechanical (3-point bend test), polymerization shrinkage (volumetric shrinkage and shrinkage stress), and antimicrobial properties (colony counting assay) against Streptococcus mutans, Streptococcus sanguinis, and Candida albicans were determined.
All experimental groups had comparable degrees of cure (near Infrared FTIR and Rockwell Hardness), TP, moduli, polymerization volumetric shrinkages and shrinkage stresses to those of controls (Bonferroni corrected p > 0.0018). Only one group (15% K18-MMA+K18-Filler) had significantly different (lower) contact angles as compared to that of controls (Bonferroni corrected p < 0.0018). Most of the K18-Filler-containing composites had significantly lower ultimate transverse strengths (UTS) than controls (Bonferroni corrected p < 0.0018). Controls had significantly greater S mutans colony counts than 15% and 20% w/w K18-MMA+K18-Filler groups, and greater S sanguinis and C albicans colony counts than K18-containing groups. Of the composites with that provided significant antimicrobial properties against S. mutans, S. sanguinis, and C. albicans, only the 20% K18-MMA+K18-Filler group had significantly lower UTS than controls.
Composites with K18-MMA and K18-Filler with comparable physical properties to control composites and significant antimicrobial properties have been developed. K18-MMA and K18-Filler seem to be suitable for incorporation into commercial dental resins.
确定使用 K18-甲基丙烯酸甲酯（K18-MMA）和 K18 填充剂对复合固化、美观、机械、聚合收缩和抗菌性能的影响。
K18-MMA（0-20%w/w）替代 TEGDMA 加入到 70:30 Bis-GMA:TEGDMA 复合树脂中，该复合树脂用钡玻璃或 K18 填充剂填充至 70%w/w。通过对复合树脂的固化程度（洛氏硬度和近红外傅里叶变换红外光谱）、亲水性（接触角测量）、透光率（透光参数测量，TP）、机械性能（三点弯曲试验）、聚合收缩（体积收缩和收缩应力）和抗菌性能（对变形链球菌、血链球菌和白色念珠菌的菌落计数试验）进行测定。
所有实验组的固化程度（近红外傅里叶变换红外光谱和洛氏硬度）、TP、模量、聚合体积收缩和收缩应力与对照组相似（Bonferroni 校正后 p＞0.0018）。只有一组（15%K18-MMA+K18 填充剂）的接触角与对照组相比显著不同（较低）（Bonferroni 校正后 p＜0.0018）。大多数含有 K18 填充剂的复合材料的最终横向强度（UTS）明显低于对照组（Bonferroni 校正后 p＜0.0018）。对照组的变形链球菌菌落计数明显高于 15%和 20%w/w K18-MMA+K18 填充剂组，血链球菌和白色念珠菌的菌落计数明显高于含 K18 的组。在对变形链球菌、血链球菌和白色念珠菌具有显著抗菌性能的复合材料中，只有 20%K18-MMA+K18 填充剂组的 UTS 明显低于对照组。
已开发出具有与对照复合树脂物理性能相当且具有显著抗菌性能的含 K18-MMA 和 K18 填充剂的复合材料。K18-MMA 和 K18 填充剂似乎适合掺入商业牙科树脂中。
