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Opportunities and Challenges for ChatGPT and Large Language Models in Biomedicine and Health.

作者信息

Tian Shubo, Jin Qiao, Yeganova Lana, Lai Po-Ting, Zhu Qingqing, Chen Xiuying, Yang Yifan, Chen Qingyu, Kim Won, Comeau Donald C, Islamaj Rezarta, Kapoor Aadit, Gao Xin, Lu Zhiyong

机构信息

National Library of Medicine, National Institutes of Health.

King Abdullah University of Science and Technology.

出版信息

ArXiv. 2023 Oct 17:arXiv:2306.10070v2.


DOI:
PMID:37904734
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10614979/
Abstract

ChatGPT has drawn considerable attention from both the general public and domain experts with its remarkable text generation capabilities. This has subsequently led to the emergence of diverse applications in the field of biomedicine and health. In this work, we examine the diverse applications of large language models (LLMs), such as ChatGPT, in biomedicine and health. Specifically we explore the areas of biomedical information retrieval, question answering, medical text summarization, information extraction, and medical education, and investigate whether LLMs possess the transformative power to revolutionize these tasks or whether the distinct complexities of biomedical domain presents unique challenges. Following an extensive literature survey, we find that significant advances have been made in the field of text generation tasks, surpassing the previous state-of-the-art methods. For other applications, the advances have been modest. Overall, LLMs have not yet revolutionized biomedicine, but recent rapid progress indicates that such methods hold great potential to provide valuable means for accelerating discovery and improving health. We also find that the use of LLMs, like ChatGPT, in the fields of biomedicine and health entails various risks and challenges, including fabricated information in its generated responses, as well as legal and privacy concerns associated with sensitive patient data. We believe this survey can provide a comprehensive and timely overview to biomedical researchers and healthcare practitioners on the opportunities and challenges associated with using ChatGPT and other LLMs for transforming biomedicine and health.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb1c/10614979/ff719f8ab86b/nihpp-2306.10070v2-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb1c/10614979/f5f06a8cdab8/nihpp-2306.10070v2-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb1c/10614979/ff719f8ab86b/nihpp-2306.10070v2-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb1c/10614979/f5f06a8cdab8/nihpp-2306.10070v2-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb1c/10614979/ff719f8ab86b/nihpp-2306.10070v2-f0002.jpg

相似文献

[1]
Opportunities and Challenges for ChatGPT and Large Language Models in Biomedicine and Health.

ArXiv. 2023-10-17

[2]
Opportunities and challenges for ChatGPT and large language models in biomedicine and health.

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[3]
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[4]
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本文引用的文献

[1]
Interactive computer-aided diagnosis on medical image using large language models.

Commun Eng. 2024-9-17

[2]
Can large language models reason about medical questions?

Patterns (N Y). 2024-3-1

[3]
Structured Prompt Interrogation and Recursive Extraction of Semantics (SPIRES): a method for populating knowledge bases using zero-shot learning.

Bioinformatics. 2024-3-4

[4]
Almanac - Retrieval-Augmented Language Models for Clinical Medicine.

NEJM AI. 2024-2

[5]
GeneGPT: augmenting large language models with domain tools for improved access to biomedical information.

Bioinformatics. 2024-2-1

[6]
ChatGPT in healthcare: A taxonomy and systematic review.

Comput Methods Programs Biomed. 2024-3

[7]
ChatGPT makes medicine easy to swallow: an exploratory case study on simplified radiology reports.

Eur Radiol. 2024-5

[8]
An extensive benchmark study on biomedical text generation and mining with ChatGPT.

Bioinformatics. 2023-9-2

[9]
Evaluating large language models on medical evidence summarization.

NPJ Digit Med. 2023-8-24

[10]
ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledge.

Cureus. 2023-6-24

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