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C-SPECT 可变狭缝堆叠准直器的分辨率和灵敏度性能评估。

Performance evaluation of resolution and sensitivity of C-SPECT's variable slat-stack collimator.

机构信息

Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

出版信息

Med Phys. 2023 Dec;50(12):7462-7477. doi: 10.1002/mp.16792. Epub 2023 Oct 31.

Abstract

BACKGROUND

Myocardial perfusion imaging is commonly performed using SPECT, where both general-purpose and dedicated scanners are available. A limitation with general-purpose systems has been the inability to image dynamically since different projections are obtained far apart in time due to scanner rotation. Dedicated systems can have this capability since they acquire completely sampled projections (i.e., those with enough angular views for reconstruction) with short time frames. C-SPECT, does not need any scanner or patient motion to obtain complete projections, allowing fast dynamics. When imaging fast dynamics, the optimal collimator settings are not necessarily the same as for static imaging, where longer acquisitions can be utilized. Thus, C-SPECT offers adaptive collimation in the transverse and axial directions.

PURPOSE

The performance of adaptation in the axial direction was characterized herein.

METHODS

The ratio of the resolution metric in high-sensitivity mode to that in the high-resolution mode, termed resolution boost factor, was determined. Analogously, the sensitivity boost factor was also determined. Comparisons were made with theory and simulations.

RESULTS

The boost factors for resolution and sensitivity, averaged over the 14 modules of the system, were determined to be 1.72 and 1.75, respectively.

CONCLUSIONS

The boost factors, which ideally would be two, were between 10% and 15% below optimal values and tracked each other, suggesting mechanical challenges in the apparatus, such as incomplete closure of adjacent slats, but show reasonably successful adaptation between modes.

摘要

背景

心肌灌注成像是常用的 SPECT 成像,其中通用型和专用型扫描仪均可使用。通用型系统的一个局限性是由于扫描仪旋转,不同的投影在时间上相隔很远,因此无法进行动态成像。专用系统可以具有这种能力,因为它们可以使用短时间帧获取完全采样的投影(即具有足够的角度视图用于重建的那些投影)。C-SPECT 不需要任何扫描仪或患者运动即可获得完整的投影,从而实现快速动态成像。在快速动态成像中,最优准直器设置不一定与静态成像相同,静态成像可以使用更长的采集时间。因此,C-SPECT 提供了在横向和轴向方向上的自适应准直。

目的

本文对轴向自适应的性能进行了描述。

方法

确定了高灵敏度模式下分辨率指标与高分辨率模式下分辨率指标的比值,称为分辨率提升因子。类似地,也确定了灵敏度提升因子。并与理论和模拟进行了比较。

结果

对系统的 14 个模块进行平均后,确定分辨率和灵敏度的提升因子分别为 1.72 和 1.75。

结论

这些提升因子(理想情况下应为 2)比最优值低 10%到 15%,并且相互跟踪,这表明设备存在机械方面的挑战,例如相邻叶片不完全关闭,但在模式之间实现了合理的自适应。

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