Institute of Medical Physics, University of Erlangen-Nürnberg, Henkestraße 91, Erlangen, Germany.
Med Phys. 2012 Apr;39(4):2249-60. doi: 10.1118/1.3697533.
Modern computed tomography (CT) systems are supporting increasingly fast rotation speeds, which are a prerequisite for fast dynamic acquisition, e.g. in perfusion imaging, and for new modalities such as dedicated breast CT, where breathhold scanning is indicated. However, not all detector technologies are supporting the high frame rates that are necessary to retain high resolution for objects far away from the isocenter. Even on systems that would support a sufficiently high frame rate, the necessary bandwidth of the data transfer from the rotating gantry stills remains challenging. The authors evaluated a pixel shifting technique termed time-delayed summation (TDS) as a method of increasing resolution on fast rotating CT systems without the need to increase the frame rate.
In TDS mode, detector pixel values are shifted along rows during image acquisition to compensate for detector motion. In order to fully exploit TDS, focal spot position control (FSC) was used in combination with TDS. FSC applies a counter movement to the x-ray focal spot during image acquisition such that it is kept fixed in space. As a proof of concept, measurements were performed on a prototype photon counting detector capable of TDS. The detector was mounted on a movable table and a gold wire phantom was imaged with different TDS settings and detector velocities. Additionally, simulations of a broad range of TDS and FSC settings on two different modalities, a clinical CT scanner and a breast CT scanner, and two different detector geometries, flat and cylindrical, were performed to assess the gain in resolution and contrast in cylindrical water phantoms containing a small wire at distances from the phantom center varied from 5% to 90% of the phantom radius. As figures of merit, the modulation transfer function (MTF) at 10% and the maximum contrast were used and compared against the respective values when using step-and-shoot acquisition, which means stopping the rotation when a projection image is acquired.
Measurements showed that detector movement and the resulting blurring of the wire projections were compensated to the expected degree when using the appropriate number of TDS shifts per frame (TDS factor). Using simulations it was found that when using the optimal TDS factor, over 90% of the resolution achieved in step-and-shot mode was reached for all investigated wire positions. TDS showed better performance on a cylindrical detector that on the same system with a flat detector. TDS factors that were deviating from the optimum by more than 1 shift led to a performance below that of standard continuous acquisition.
The findings of this study encourage the combined usage of TDS and FSC in systems that require fast rotation. The integration of TDS in state-of-the-art x-ray detectors is feasible.
现代计算机断层扫描(CT)系统支持越来越快的旋转速度,这是快速动态采集的前提,例如在灌注成像中,以及在专用乳腺 CT 等新模态中,需要屏气扫描。然而,并非所有的探测器技术都支持为保持远离等中心的物体的高分辨率所需的高帧率。即使在支持足够高帧率的系统上,从旋转机架传输数据的必要带宽仍然具有挑战性。作者评估了一种称为时间延迟求和(TDS)的像素移位技术,作为一种在不需要增加帧率的情况下提高快速旋转 CT 系统分辨率的方法。
在 TDS 模式下,在图像采集过程中,探测器像素值沿行移动以补偿探测器运动。为了充分利用 TDS,在 TDS 模式下使用焦点位置控制(FSC)。FSC 在图像采集过程中对 X 射线焦点施加反向运动,使其在空间中保持固定。作为概念验证,在能够进行 TDS 的光子计数探测器原型上进行了测量。探测器安装在可移动的桌子上,并用金丝体模进行成像,使用不同的 TDS 设置和探测器速度。此外,对两种不同的模态(临床 CT 扫描仪和乳腺 CT 扫描仪)和两种不同的探测器几何形状(平面和圆柱形)进行了广泛的 TDS 和 FSC 设置的模拟,以评估在圆柱形水体模中包含小金属丝的距离从体模中心的 5%到 90%的情况下分辨率和对比度的增益。作为衡量标准,使用调制传递函数(MTF)在 10%和最大对比度,并将其与使用逐点采集(当采集投影图像时停止旋转)时的相应值进行比较。
测量结果表明,当使用每一帧的适当数量的 TDS 移位(TDS 因子)时,探测器运动和由此产生的金属丝投影模糊得到了预期的补偿。通过模拟发现,当使用最佳 TDS 因子时,在所研究的所有金属丝位置,都达到了逐点采集模式下实现的超过 90%的分辨率。TDS 在圆柱形探测器上的性能优于在相同系统上的平面探测器。偏离最佳值超过 1 个移位的 TDS 因子会导致性能低于标准连续采集。
本研究的结果鼓励在需要快速旋转的系统中结合使用 TDS 和 FSC。在最先进的 X 射线探测器中集成 TDS 是可行的。