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自适应单光子发射计算机断层成像孔径

The AdaptiSPECT Imaging Aperture.

作者信息

Chaix Cécile, Moore Jared W, Van Holen Roel, Barrett Harrison H, Furenlid Lars R

机构信息

College of Optical Sciences, University of Arizona.

Department of Electronics and Information Systems, Ghent University, Belgium.

出版信息

IEEE Nucl Sci Symp Conf Rec (1997). 2012 Oct-Nov;2012:3564-3567. doi: 10.1109/NSSMIC.2012.6551816.

DOI:10.1109/NSSMIC.2012.6551816
PMID:27019577
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4807117/
Abstract

In this paper, we present the imaging aperture of an adaptive SPECT imaging system being developed at the Center for Gamma Ray Imaging (AdaptiSPECT). AdaptiSPECT is designed to automatically change its configuration in response to preliminary data, in order to improve image quality for a particular task. In a traditional pinhole SPECT imaging system, the characteristics (magnification, resolution, field of view) are set by the geometry of the system, and any modification can be accomplished only by manually changing the collimator and the distance of the detector to the center of the field of view. Optimization of the imaging system for a specific task on a specific individual is therefore difficult. In an adaptive SPECT imaging system, on the other hand, the configuration can be conveniently changed under computer control. A key component of an adaptive SPECT system is its aperture. In this paper, we present the design, specifications, and fabrication of the adaptive pinhole aperture that will be used for AdaptiSPECT, as well as the controls that enable autonomous adaptation.

摘要

在本文中,我们介绍了伽马射线成像中心(AdaptiSPECT)正在研发的自适应单光子发射计算机断层扫描(SPECT)成像系统的成像孔径。AdaptiSPECT旨在根据初步数据自动改变其配置,以提高特定任务的图像质量。在传统的针孔SPECT成像系统中,其特性(放大倍数、分辨率、视野)由系统的几何结构设定,任何修改都只能通过手动更换准直器以及探测器到视野中心的距离来实现。因此,针对特定个体的特定任务对成像系统进行优化很困难。另一方面,在自适应SPECT成像系统中,配置可以在计算机控制下方便地改变。自适应SPECT系统的一个关键部件是其孔径。在本文中,我们介绍了将用于AdaptiSPECT的自适应针孔孔径的设计、规格和制造,以及实现自主适应的控制方法。

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本文引用的文献

1
Adaptive SPECT for Tumor Necrosis Detection.用于肿瘤坏死检测的自适应单光子发射计算机断层扫描
IEEE Nucl Sci Symp Conf Rec (1997). 2008 Oct;2008:5548-5551. doi: 10.1109/NSSMIC.2008.4774505.
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ADAPTIVE SMALL-ANIMAL SPECT/CT.自适应小动物单光子发射计算机断层扫描/计算机断层扫描
IEEE Nucl Sci Symp Conf Rec (1997). 2008;2008:1407-1410. doi: 10.1109/ISBI.2008.4541269.
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Design and Validation of an Adaptive SPECT System: AdaptiSPECT.一种自适应单光子发射计算机断层扫描系统的设计与验证:AdaptiSPECT
IEEE Nucl Sci Symp Conf Rec (1997). 2010;2010:2539-2544. doi: 10.1109/NSSMIC.2010.5874245. Epub 2010 Oct 30.
4
Novel Applications of Rapid Prototyping in Gamma-ray and X-ray Imaging.快速成型技术在伽马射线和X射线成像中的新应用
IEEE Nucl Sci Symp Conf Rec (1997). 2009 Oct 24;2009:3322-3326. doi: 10.1109/NSSMIC.2009.5401745.
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FastSPECT II: A Second-Generation High-Resolution Dynamic SPECT Imager.快速单光子发射计算机断层扫描II:第二代高分辨率动态单光子发射计算机断层扫描仪
IEEE Trans Nucl Sci. 2004 Jun;51(3):631-635. doi: 10.1109/TNS.2004.830975.
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A prototype instrument for single pinhole small animal adaptive SPECT imaging.一种用于单针孔小动物自适应单光子发射计算机断层显像(SPECT)成像的原型仪器。
Med Phys. 2008 May;35(5):1912-25. doi: 10.1118/1.2896072.
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