, Forstmeisterweg 65, D-23568, Lübeck, Germany.
, Iburger Straße 116, D-49082, Osnabrück, Germany.
Int J Colorectal Dis. 2023 Oct 31;38(1):261. doi: 10.1007/s00384-023-04555-x.
This study aims to compare the outcomes of repair/redo ileal pouch-anal anastomosis (repair/redo-IPAA) with the conversion of IPAA to continent ileostomy (CI) in an effort to prevent the need for a permanent ileostomy (IS) following IPAA failure.
This research involved a retrospective analysis of surgical records, employing descriptive statistics and Kaplan-Meier survival analysis.
Among 57 patients with an IPAA, up to three revisions were necessary due to complications or complete failure. Ultimately, repair/redo-IPAA preserved the IPAA in 14 patients (24.6%), conversion to CI salvaged the pouch in 21 patients (36.8%), and IS was unavoidable in 22 patients (38.6%). The cumulative probability of requiring conversion surgery was calculated to be 54.0% at 20 years, thereby reducing the cumulative risk of IS to 32.3%. The 20-year cumulative probability of pouch salvage by repair/redo IPAA was only 21.9%. However, this rate increased to 67.7% when conversion procedures were considered. Following repair/redo-IPAA, only 8.3% of patients reported evacuation frequencies of ≤ 4 during the day, and 16.7% were evacuation-free at night. In contrast, after conversion to CI, 98.0% of patients reported a maximum of four evacuations in a 24-h period. After undergoing repair/redo IPAA, between half and two-thirds of patients reported experiencing incontinence or soiling, while complete continence was achieved in all patients following conversion to CI. Notably, the majority of patients expressed overall satisfaction with their respective procedures. A positive correlation was identified between very high subjective satisfaction and positive objective surgical outcomes exclusively in patients who underwent conversion to CI.
When complications or failure of IPAA occur, conversion to CI emerges as a highly viable alternative to repair/redo IPAA. This conclusion is supported by the observation that patient satisfaction appears to be closely tied to stable surgical outcomes. To reinforce these findings, further prospective studies are warranted.
本研究旨在比较修复/翻修回肠贮袋肛管吻合术(修复/翻修-IPAA)与 IPAA 转为 continent ileostomy(CI)的结果,以防止 IPAA 失败后需要永久性 ileostomy(IS)。
本研究对手术记录进行回顾性分析,采用描述性统计和 Kaplan-Meier 生存分析。
在 57 例 IPAA 患者中,由于并发症或完全失败,需要进行多达三次修正。最终,修复/翻修-IPAA 保留了 14 例患者(24.6%)的 IPAA,转换为 CI 挽救了 21 例患者(36.8%)的贮袋,22 例患者(38.6%)无法避免 IS。计算出 20 年内需要转换手术的累积概率为 54.0%,从而将 IS 的累积风险降低至 32.3%。通过修复/翻修 IPAA 进行贮袋挽救的 20 年累积概率仅为 21.9%。然而,当考虑到转换程序时,这一比率增加到 67.7%。在修复/翻修-IPAA 后,只有 8.3%的患者报告白天排便频率≤4 次,16.7%的患者夜间无排便。相比之下,在转换为 CI 后,98.0%的患者报告在 24 小时内最多有 4 次排便。在接受修复/翻修 IPAA 后,有一半到三分之二的患者报告出现失禁或污粪,而所有患者在转换为 CI 后均获得完全控便。值得注意的是,大多数患者对各自的手术过程表示满意。只有在接受转换为 CI 的患者中,非常高的主观满意度与积极的客观手术结果之间存在正相关关系。
当 IPAA 出现并发症或失败时,转换为 CI 是修复/翻修 IPAA 的一个极具可行性的替代方案。这一结论得到了以下观察结果的支持:患者满意度似乎与稳定的手术结果密切相关。为了加强这些发现,需要进行进一步的前瞻性研究。