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恒河猴(猕猴)生精上皮周期的持续时间及其阶段

Duration of the cycle of the seminiferous epithelium and its stages in the rhesus monkey (Macaca mulatta).

作者信息

de Rooij D G, van Alphen M M, van de Kant H J

出版信息

Biol Reprod. 1986 Oct;35(3):587-91. doi: 10.1095/biolreprod35.3.587.

DOI:10.1095/biolreprod35.3.587
PMID:3790660
Abstract

Doses of 1 Gy or more of X-irradiation killed all B spermatogonia present in the testis, and during the first 3 weeks after irradiation, virtually no new B spermatogonia were formed. The number of Apale spermatogonia decreased during the first cycle of the seminiferous epithelium while the number of Adark spermatogonia only began to decrease during the second cycle after irradiation. In this study, the duration of the cycle of the seminiferous epithelium in the rhesus monkey was estimated to be 10.5 days (SE = 0.2 days). This was determined following the depletion of germinal cells in the seminiferous epithelium during the first 3 weeks after irradiation. The duration of each of the 12 stages of the cycle was also determined. Our observations of the progress of germinal cell depletion revealed that after a dose of X-irradiation sufficient to kill all B spermatogonia, all spermatocytes disappeared from the testis within about 17 days, and all spermatids within about 31 days.

摘要

1戈瑞或更高剂量的X射线照射可杀死睾丸中所有的B型精原细胞,并且在照射后的前3周内,几乎没有新的B型精原细胞形成。浅色A1型精原细胞的数量在生精上皮的第一个周期中减少,而深色A2型精原细胞的数量仅在照射后的第二个周期开始减少。在本研究中,恒河猴生精上皮周期的持续时间估计为10.5天(标准误 = 0.2天)。这是在照射后的前3周生精上皮中的生殖细胞耗竭后确定的。还确定了周期12个阶段中每个阶段的持续时间。我们对生殖细胞耗竭过程的观察表明,在给予足以杀死所有B型精原细胞的X射线剂量后,所有精母细胞在约17天内从睾丸中消失,所有精子细胞在约31天内消失。

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