• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用于治疗心力衰竭的钠-葡萄糖协同转运蛋白2抑制剂

[Sodium-glucose cotransporter 2 inhibitors for the management of heart failure].

作者信息

Nouel Ana, Winter José Luis, Sepúlveda Luis

机构信息

Departamento de Enfermedades Cardiovasculares, Clínica Alemana de Santiago, Santiago, Chile.

出版信息

Rev Med Chil. 2022 Dec;150(12):1647-1654. doi: 10.4067/s0034-98872022001201647.

DOI:10.4067/s0034-98872022001201647
PMID:37906786
Abstract

Heart failure (HF) is a global health problem. There is a strong association h between HF and type 2 diabetes mellitus (DM2), with an increasing prevalence of patients having both conditions concomitantly. Sodium-glucose cotransporter 2 inhibitors (ISGLT2) significantly reduce cardiovascular events, including cardiovascular death. In this article we will focus on the current evidence about the effectiveness of these medications in adults with heart failure with reduced or preserved ejection fraction.

摘要

心力衰竭(HF)是一个全球性的健康问题。HF与2型糖尿病(DM2)之间存在密切关联,同时患有这两种疾病的患者患病率不断上升。钠-葡萄糖协同转运蛋白2抑制剂(SGLT2)可显著降低心血管事件,包括心血管死亡。在本文中,我们将重点关注这些药物对射血分数降低或保留的成年心力衰竭患者有效性的现有证据。

相似文献

1
[Sodium-glucose cotransporter 2 inhibitors for the management of heart failure].用于治疗心力衰竭的钠-葡萄糖协同转运蛋白2抑制剂
Rev Med Chil. 2022 Dec;150(12):1647-1654. doi: 10.4067/s0034-98872022001201647.
2
Use of Sodium-Glucose Cotransporter-2 Inhibitors in Clinical Practice for Heart Failure Prevention and Treatment: Beyond Type 2 Diabetes. A Narrative Review.钠-葡萄糖共转运蛋白 2 抑制剂在心力衰竭预防和治疗中的临床应用:超越 2 型糖尿病。一篇叙述性综述。
Adv Ther. 2022 Feb;39(2):845-861. doi: 10.1007/s12325-021-01989-z. Epub 2021 Dec 9.
3
Effect of Empagliflozin on Left Ventricular Volumes in Patients With Type 2 Diabetes, or Prediabetes, and Heart Failure With Reduced Ejection Fraction (SUGAR-DM-HF).恩格列净对射血分数降低的心力衰竭合并 2 型糖尿病或糖尿病前期患者左心室容积的影响(SUGAR-DM-HF)。
Circulation. 2021 Feb 9;143(6):516-525. doi: 10.1161/CIRCULATIONAHA.120.052186. Epub 2020 Nov 13.
4
Egyptian expert opinion for the use of sodium-glucose cotransporter-2 inhibitors in patients with heart failure with reduced ejection fraction.埃及专家关于钠-葡萄糖共转运蛋白 2 抑制剂在射血分数降低的心力衰竭患者中的应用的意见。
ESC Heart Fail. 2022 Apr;9(2):800-811. doi: 10.1002/ehf2.13811. Epub 2022 Feb 3.
5
Sodium-glucose cotransporter 2 inhibitors in heart failure with preserved ejection fraction: A protocol for meta-analysis.钠-葡萄糖共转运蛋白 2 抑制剂在射血分数保留的心力衰竭中的应用:荟萃分析方案。
Medicine (Baltimore). 2021 Dec 23;100(51):e28448. doi: 10.1097/MD.0000000000028448.
6
Comparative effectiveness of sodium-glucose cotransporter-2 inhibitors among patients with heart failure with preserved ejection fraction.钠-葡萄糖共转运蛋白 2 抑制剂在射血分数保留的心力衰竭患者中的疗效比较。
Pharmacotherapy. 2023 Oct;43(10):1024-1031. doi: 10.1002/phar.2853. Epub 2023 Jul 23.
7
SGLT2 Inhibitors and Heart Failure with Preserved Ejection Fraction.钠-葡萄糖协同转运蛋白 2 抑制剂与射血分数保留的心力衰竭。
Heart Fail Clin. 2022 Oct;18(4):579-586. doi: 10.1016/j.hfc.2022.03.010.
8
Baseline Characteristics of Patients With HF With Mildly Reduced and Preserved Ejection Fraction: DELIVER Trial.射血分数轻度降低和保留的心力衰竭患者的基线特征:DELIVER试验
JACC Heart Fail. 2022 Mar;10(3):184-197. doi: 10.1016/j.jchf.2021.11.006.
9
Sodium-glucose co-transporter 2 inhibitors: drugs with multiple effects, but which one is relevant to heart failure with preserved ejection fraction? Letter regarding the article 'Early benefit with empagliflozin in heart failure with preserved ejection fraction: insights from the EMPEROR-Preserved trial'.钠-葡萄糖协同转运蛋白2抑制剂:具有多种作用的药物,但哪一种与射血分数保留的心力衰竭相关?关于文章《恩格列净对射血分数保留的心力衰竭的早期获益:EMPEROR-Preserved试验的见解》的信函
Eur J Heart Fail. 2022 Jul;24(7):1323-1324. doi: 10.1002/ejhf.2466. Epub 2022 Mar 9.
10
Sodium-Glucose Cotransporter-2 inhibitors are potential therapeutic agents for treatment of non-diabetic heart failure patients.钠-葡萄糖共转运蛋白 2 抑制剂是治疗非糖尿病心力衰竭患者的潜在治疗药物。
J Cardiol. 2020 Aug;76(2):123-131. doi: 10.1016/j.jjcc.2020.03.009. Epub 2020 Apr 24.

引用本文的文献

1
Use of Acetazolamide in People with Decompensated Heart Failure: A Systematic Review and Meta-Analysis.乙酰唑胺在失代偿性心力衰竭患者中的应用:一项系统评价和荟萃分析。
Curr Cardiol Rep. 2025 Jun 23;27(1):99. doi: 10.1007/s11886-025-02257-0.