Simonassi Julia Inés, Canzobre María Tatiana
Hospital Nacional de Pediatría Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina.
Andes Pediatr. 2022 Aug;93(4):543-551. doi: 10.32641/andespediatr.v93i4.4155.
Upper airway obstruction after extubation is a serious complication that can lead to extubation fai lure and other unfavorable outcomes in children.
to describe the incidence and risk fac tors associated with post-extubation upper airway obstruction in critically ill children.
A prospective descriptive observational study was carried out in a pediatric intensive care unit in Argentina over two years. Patients older than 1 month and younger than 18 years, receiving mechanical ventilatory support (MV) for more than 24 hours through an endotracheal tube (ETT) and with at least one programmed extubation were included.
Of 260 patients, 65 (25%) de veloped post-extubation upper obstruction. Of them, 37 were females (56.9%), with a median age of 14 months and 10 kg weight. The PIM3 score was 2.8 and the most frequent reason for admission was acute lower respiratory infection in 38 (43.1%) patients, among whom 36 (55.4%) had at least one complex chronic condition. Twenty-seven (41.5%) failed extubation and 5 (7.7%) required tracheos tomy. A multiple logistic regression analysis was performed to determine the relationship between different variables with the dependent variable. Independent risk factors explaining post-extubation upper obstruction were age ≤ 24 months and MV support for ≤ 3 days.
Post-extubation upper airway obstruction is frequent in the pediatric intensive care unit. We found that infants and mechanical ventilation duration less than or equal to 3 days are independent risk factors for its pre sentation.
拔管后上气道梗阻是一种严重并发症,可导致儿童拔管失败及其他不良后果。
描述危重症儿童拔管后上气道梗阻的发生率及相关危险因素。
在阿根廷一家儿科重症监护病房进行了一项为期两年的前瞻性描述性观察研究。纳入年龄大于1个月且小于18岁、通过气管内插管接受机械通气支持超过24小时且至少有一次计划拔管的患者。
260例患者中,65例(25%)发生拔管后上气道梗阻。其中,37例为女性(56.9%),中位年龄14个月,体重10千克。小儿死亡风险指数3(PIM3)评分为2.8,最常见的入院原因是急性下呼吸道感染,共38例(43.1%),其中36例(55.4%)至少有一种复杂慢性病。27例(41.5%)拔管失败,5例(7.7%)需要气管切开。进行多因素logistic回归分析以确定不同变量与因变量之间的关系。解释拔管后上气道梗阻的独立危险因素为年龄≤24个月及机械通气支持≤3天。
拔管后上气道梗阻在儿科重症监护病房很常见。我们发现婴儿及机械通气时间小于或等于3天是其发生的独立危险因素。