Alvarado-León Jimena, Cifuentes-Silva Eduardo, Encalada-Parra Alejandra, Bueno-Buker Daniel
Hospital Dr. Exequiel González Cortes, Santiago, Chile.
Andes Pediatr. 2022 Oct;93(5):648-657. doi: 10.32641/andespediatr.v93i5.4094.
In June 2020 appeared the first cases of Multisystem Inflammatory Syndrome in Children (MIS C) associated with COVID-19 in Chile. Possible sequelae associated with this condition are still unknown.
To describe the functional status of children with MIS-C admitted to a high complexity Hospital.
Descriptive, prospective study. Sample of 28 patients. The functional status was evaluated during Hospitalization, and in the first and fourth months after discharge with the Functional Status Scale (FSS), Pediatric Evaluation of Disability Inventory (PEDI- CAT), 6-minute walk test (6MWT), PImax and PEmax, and dynamometry. Post-Traumatic Stress Disorder was screened with the Child PTSD Symptom Scale (CPSS).
Mean age 63.6 months. Sixteen were women and 60.7% presented no comorbidities. Half of the cases presented with Shock. Mean hospitalization was 9 days. Twenty-two patients were admitted to the ICU; 54% required me chanical ventilation and/or vasoactive drugs, and 82% had cardiac repercussions. During hospitaliza tion, 82.3% presented some physical alteration, 29.1% of them were confirmed ICU-acquired weak ness (ICU-AW), and 16.6% were suspected cases. Thirteen patients presented emotional symptoms, 39.2% had post-ICU syndrome. Most of the patients (58.8%) had an unfavorable Functional Situa tion and recovered 4 months post-discharge. All patients reversed echocardiographic abnormalities in the first month and regained muscle strength in the fourth month. 38.5% of subjects reported su boptimal values in the 6MWT and 66.6% presented alteration in the post-traumatic stress screening.
Most of the patients presented functional compromise with favorable recovery despite the severity of the symptoms and possible secondary complications after ICU.
2020年6月，智利出现了首例与新冠病毒相关的儿童多系统炎症综合征（MIS-C）病例。与该病症相关的可能后遗症仍不明确。
描述入住一家高复杂性医院的MIS-C患儿的功能状况。
描述性前瞻性研究。样本为28名患者。在住院期间、出院后第一个月和第四个月，使用功能状态量表（FSS）、儿童残疾评估量表（PEDI-CAT）、6分钟步行试验（6MWT）、最大吸气压力（PImax）和最大呼气压力（PEmax）以及握力测量来评估功能状态。使用儿童创伤后应激障碍症状量表（CPSS）对创伤后应激障碍进行筛查。
平均年龄63.6个月。16名女性，60.7%无合并症。半数病例出现休克。平均住院时间为9天。22名患者入住重症监护病房（ICU）；54%需要机械通气和/或血管活性药物，82%有心脏影响。住院期间，82.3%出现某种身体改变，其中29.1%被确诊为ICU获得性肌无力（ICU-AW），16.6%为疑似病例。13名患者出现情绪症状，39.2%有ICU后综合征。大多数患者（58.8%）功能状况不佳，出院后4个月恢复。所有患者在第一个月心脏超声异常均得到逆转，在第四个月恢复肌肉力量。38.5%的受试者6MWT值未达最佳，66.6%在创伤后应激筛查中出现改变。
尽管症状严重且ICU后可能有继发并发症，但大多数患者功能受损后恢复良好。
