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下颌骨后部的成釉细胞纤维牙瘤:一种罕见的病理实体。

Ameloblastic Fibro-Odontoma of the Posterior Mandible: A Rare Pathological Entity.

作者信息

Goel Mahima, Qamar Ali, Daftary Mimansa, Chhabile Sujata, Pundkar Shruti

机构信息

Department of Oral and Maxillofacial Surgery, Pacific Dental College and Research Centre, Udaipur, IND.

Department of Oral and Maxillofacial Surgery, Teerthankar Mahaveer Dental College and Research Institute, Moradabad, IND.

出版信息

Cureus. 2023 Sep 30;15(9):e46264. doi: 10.7759/cureus.46264. eCollection 2023 Sep.

DOI:10.7759/cureus.46264
PMID:37908930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10615230/
Abstract

Ameloblastic fibro-odontoma (AFO) is a rare, slow-growing neoplastic lesion classified as a benign, epithelial mixed odontogenic tumor with odontogenic mesenchyme. This tumor demonstrates the histological features characteristic of both ameloblastic fibromas and complex odontomas. The clinical manifestation of AFO is typically characterized by asymptomatic enlargement of the jawbones. Radiographically, it presents as a distinct radiolucent region, indicating the presence of radiopaque substances with varying degrees of irregularities in size and morphology. Standard therapeutic intervention involves enucleation. Despite its benign nature, AFO can cause significant morbidity if left untreated. Therefore, prompt diagnosis and appropriate management are essential to ensure optimal patient outcomes. The following case report details the clinical presentation and management of an 18-year-old male with an AFO lesion located in the posterior mandible. This particular case was treated with conservative measures involving surgical enucleation.

摘要

成釉细胞纤维牙瘤(AFO)是一种罕见的、生长缓慢的肿瘤性病变,归类为良性上皮性混合牙源性肿瘤,伴有牙源性间充质。该肿瘤具有成釉细胞纤维瘤和复合性牙瘤的典型组织学特征。AFO的临床表现通常为颌骨无症状性肿大。在影像学上,它表现为一个明显的透射区,提示存在大小和形态各异的不透射线物质。标准的治疗干预措施是摘除术。尽管AFO本质上是良性的,但如果不治疗,可能会导致严重的发病情况。因此,及时诊断和恰当处理对于确保患者获得最佳预后至关重要。以下病例报告详细介绍了一名18岁男性下颌后部患有AFO病变的临床表现及治疗情况。该特殊病例采用了包括手术摘除在内的保守治疗措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfa/10615230/4dc8d1d69144/cureus-0015-00000046264-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfa/10615230/2895d42d8559/cureus-0015-00000046264-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfa/10615230/f09734890dac/cureus-0015-00000046264-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfa/10615230/3e30fb89c28f/cureus-0015-00000046264-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfa/10615230/4dc8d1d69144/cureus-0015-00000046264-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfa/10615230/2895d42d8559/cureus-0015-00000046264-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfa/10615230/f09734890dac/cureus-0015-00000046264-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfa/10615230/3e30fb89c28f/cureus-0015-00000046264-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bfa/10615230/4dc8d1d69144/cureus-0015-00000046264-i04.jpg

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本文引用的文献

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Ameloblastic fibroma: A case report.成釉细胞纤维瘤:一例病例报告。
J Oral Maxillofac Pathol. 2023 Feb;27(Suppl 1):S60-S63. doi: 10.4103/jomfp.jomfp_337_22. Epub 2023 Feb 4.
2
A Locally Aggressive Ameloblastic Fibro-Odontoma: A Case Report and Literature Review.一例局部侵袭性成釉细胞纤维牙瘤:病例报告及文献综述
Cureus. 2021 Dec 12;13(12):e20366. doi: 10.7759/cureus.20366. eCollection 2021 Dec.
3
Ameloblastic Fibro-Odontoma: At the Crossroad Between "Developing Odontoma" and True Odontogenic Tumour.成釉纤维牙瘤:位于“发育性牙瘤”和真正牙源性肿瘤之间的十字路口。
Head Neck Pathol. 2021 Dec;15(4):1202-1211. doi: 10.1007/s12105-021-01332-6. Epub 2021 May 15.
4
Ameloblastic fibro-odontoma associated with paresthesia of the chin and lower lip in a 12-year-old girl.一名12岁女孩患成釉细胞纤维牙瘤并伴有颏部及下唇感觉异常。
SAGE Open Med Case Rep. 2019 Aug 14;7:2050313X19870642. doi: 10.1177/2050313X19870642. eCollection 2019.
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A Rare Case of Ameloblastic Fibro-Odontoma of Mandible with Literature Review.下颌骨成釉细胞纤维牙瘤1例并文献复习
Ann Maxillofac Surg. 2018 Jul-Dec;8(2):324-326. doi: 10.4103/ams.ams_127_18.
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Ameloblastic Fibrodentinoma: A Rarity in Odontogenic Tumors.成釉细胞纤维牙本质瘤:牙源性肿瘤中的罕见病例。
J Maxillofac Oral Surg. 2018 Dec;17(4):444-448. doi: 10.1007/s12663-017-1062-3. Epub 2017 Dec 14.
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Odontoameloblastoma: A report of a rare case.牙源性成釉细胞瘤:1例罕见病例报告
J Oral Maxillofac Pathol. 2018 May-Aug;22(2):254-259. doi: 10.4103/jomfp.JOMFP_192_17.
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The World Health Organization Classification of Odontogenic Lesions: A Summary of the Changes of the 2017 (4th) Edition.世界卫生组织牙源性病变分类:2017年(第4版)变化总结
Turk Patoloji Derg. 2018;34(1). doi: 10.5146/tjpath.2017.01410.
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Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Odontogenic and Maxillofacial Bone Tumors.世界卫生组织头颈部肿瘤分类第4版更新:牙源性和颌面骨肿瘤
Head Neck Pathol. 2017 Mar;11(1):68-77. doi: 10.1007/s12105-017-0794-1. Epub 2017 Feb 28.
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