Birdal Oğuzhan, Saygı Mehmet, Doğan Remziye, Pay Levent, Aksakal Emrah, Topaloğlu Caner, Yıldırım Mustafa, Aksu Uğur
Department of Cardiology, Atatürk University Faculty of Medicine, Erzurum, Türkiye.
Department of Cardiology, Hisar Intercontinental Hospital, İstanbul, Türkiye.
Eurasian J Med. 2023 Oct;55(3):249-253. doi: 10.5152/eurasianjmed.2023.23235.
Based on several studies, atrial remodeling results in an increase in left atrial (LA) stiffness, which is indicative of a worsened reservoir function. A typical microvascular consequence of diabetes mellitus (DM) is diabetic retinopathy. Therefore, the objective of this study was to assess the factors that might be related to LA stiffness in DM patients.
There were 200 DM patients in the study population. The LA stiffness value of 0.33 led to the division of the patients into 2 groups. According to these groups, the parameters to predict the development of the LA stiffness were investigated.
The patient population's median age was 54.7 ± 9.4 years, and of them, 105 (52.5% of the population) were men. Retinopathy was substantially linked with LA stiffness. Interventricular septum thickness (B coefficient: 0.261, 95% CI 0.128; 0.394; P < .001), mitral annular plane systolic excursion (B coefficient: -0.350, 95% CI -0.489; -0.2212; P < 0.001), and retinopathy (B coefficient: 0.644, 95% CI 0.307; 0.983; P < .001) were identified as independent predictors of the progression of LA stiffness by the linear regression model.
The results of the current investigation demonstrated a correlation between higher LA stiffness values and the presence of diabetic retinopathy in diabetic patients.
基于多项研究，心房重构会导致左心房（LA）僵硬度增加，这表明心房储器功能恶化。糖尿病（DM）的一个典型微血管并发症是糖尿病视网膜病变。因此，本研究的目的是评估可能与DM患者LA僵硬度相关的因素。
研究人群中有200例DM患者。LA僵硬度值为0.33，据此将患者分为两组。根据这些分组，研究预测LA僵硬度发展的参数。
患者人群的中位年龄为54.7±9.4岁，其中105例（占人群的52.5%）为男性。视网膜病变与LA僵硬度密切相关。线性回归模型确定室间隔厚度（B系数：0.261，95%CI 0.128；0.394；P<.001）、二尖瓣环平面收缩期位移（B系数：-0.350，95%CI -0.489；-0.2212；P<0.001）和视网膜病变（B系数：0.644，95%CI 0.307；0.983；P<.001）是LA僵硬度进展的独立预测因素。
当前研究结果表明，糖尿病患者较高的LA僵硬度值与糖尿病视网膜病变的存在之间存在相关性。
