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子宫肌瘤与生育能力。

Fibroids and Fertility.

机构信息

Department of OBGYN, University of Chicago Medicine, OBGYN/N101, 5841 South Maryland Avenue, Chicago, IL 60637, USA.

Private Clinic of Obstetrics and Gynecology, Asbahi Street, Sana'a, Republic of Yemen.

出版信息

Obstet Gynecol Clin North Am. 2023 Dec;50(4):663-675. doi: 10.1016/j.ogc.2023.08.006. Epub 2023 Oct 3.

DOI:10.1016/j.ogc.2023.08.006
PMID:37914486
Abstract

Uterine fibroids significantly impact women's reproductive health, influencing fertility potential and pregnancy outcomes. Their growth, often facilitated by hormonal influences like estrogen and progesterone, can cause considerable disruptions in the uterus, leading to symptoms and complications that impact the quality of life and reproductive prospects of women.This article provides an exhaustive discussion of uterine fibroids, including pathophysiology, their impact on endometrial function, receptivity, fertility, and pregnancy outcomes, and the management of infertility in patients with uterine fibroids. It underlines the critical role of uterine fibroids in women's reproductive health, emphasizing the importance of effective diagnosis and treatment to promote fertility and improve pregnancy outcomes.

摘要

子宫肌瘤会显著影响女性的生殖健康,影响生育能力和妊娠结局。它们的生长通常受到雌激素和孕激素等激素的影响,会导致子宫出现严重的紊乱,引起症状和并发症,影响女性的生活质量和生殖前景。本文全面讨论了子宫肌瘤,包括其病理生理学、对子宫内膜功能、容受性、生育能力和妊娠结局的影响,以及子宫肌瘤患者不孕的管理。它强调了子宫肌瘤在女性生殖健康中的关键作用,强调了有效诊断和治疗以促进生育和改善妊娠结局的重要性。

相似文献

1
Fibroids and Fertility.子宫肌瘤与生育能力。
Obstet Gynecol Clin North Am. 2023 Dec;50(4):663-675. doi: 10.1016/j.ogc.2023.08.006. Epub 2023 Oct 3.
2
The management of uterine fibroids in women with otherwise unexplained infertility.患有不明原因不孕症的女性子宫肌瘤的管理。
J Obstet Gynaecol Can. 2015 Mar;37(3):277-285. doi: 10.1016/S1701-2163(15)30318-2.
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The management of uterine leiomyomas.子宫平滑肌瘤的管理
J Obstet Gynaecol Can. 2015 Feb;37(2):157-178. doi: 10.1016/S1701-2163(15)30338-8.
4
Uterine fibroids and subfertility: an update on the role of myomectomy.子宫肌瘤与不孕:子宫肌瘤切除术作用的最新研究进展。
Curr Opin Obstet Gynecol. 2013 Jun;25(3):255-9. doi: 10.1097/GCO.0b013e3283612188.
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The impact of uterine leiomyomas on reproductive outcomes.子宫平滑肌瘤对生殖结局的影响。
Minerva Ginecol. 2010 Jun;62(3):225-36.
6
Dealing with uterine fibroids in reproductive medicine.生殖医学中子宫肌瘤的处理
J Obstet Gynaecol. 2012 Apr;32(3):210-6. doi: 10.3109/01443615.2011.644357.
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Management of uterine fibroids in the patient pursuing assisted reproductive technologies.接受辅助生殖技术治疗的子宫肌瘤患者的管理
Womens Health (Lond). 2009 Jul;5(4):413-21. doi: 10.2217/whe.09.29.
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Fibroids and in-vitro fertilization: which comes first?子宫肌瘤与体外受精:何者为先?
Curr Opin Obstet Gynecol. 2005 Jun;17(3):225-31. doi: 10.1097/01.gco.0000169097.52848.ee.
9
A randomised trial of treating fibroids with either embolisation or myomectomy to measure the effect on quality of life among women wishing to avoid hysterectomy (the FEMME study): study protocol for a randomised controlled trial.一项关于使用栓塞术或子宫肌瘤切除术治疗子宫肌瘤以衡量对希望避免子宫切除术的女性生活质量影响的随机试验(FEMME研究):一项随机对照试验的研究方案
Trials. 2014 Nov 29;15:468. doi: 10.1186/1745-6215-15-468.
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Therapeutic management of uterine fibroid tumors: updated French guidelines.子宫纤维瘤肿瘤的治疗管理:法国更新指南。
Eur J Obstet Gynecol Reprod Biol. 2012 Dec;165(2):156-64. doi: 10.1016/j.ejogrb.2012.07.030. Epub 2012 Aug 29.

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JMIR Form Res. 2025 Aug 1;9:e75120. doi: 10.2196/75120.
2
Integrated pharmacoanalysis, bioinformatics analysis, and experimental validation to identify the ingredients and mechanisms of Xiao-Luo-Wan in uterine fibroids treatment.综合药物分析、生物信息学分析和实验验证,以确定消瘤丸治疗子宫肌瘤的成分和作用机制。
Pharm Biol. 2025 Dec;63(1):201-217. doi: 10.1080/13880209.2025.2485905. Epub 2025 Apr 12.
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Uterine Leiomyomas and Infertility: A Comparison of National and International Guidelines.
子宫平滑肌瘤与不孕症:国内外指南比较
Cureus. 2023 Dec 23;15(12):e50992. doi: 10.7759/cureus.50992. eCollection 2023 Dec.